Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | adenosylhomocysteinase | 0.1216 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.1216 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0085 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.1216 | 1 | 1 |
Plasmodium falciparum | adenosylhomocysteinase | 0.1216 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.1216 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0085 | 0.0299 | 0.0299 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0753 | 0.6024 | 0.6024 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0299 | 0.0239 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.1216 | 1 | 0.5 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0155 | 0.0903 | 0.0847 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.1216 | 1 | 1 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.1216 | 1 | 0.5 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.1216 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0382 | 0.2843 | 0.2623 |
Schistosoma mansoni | adenosylhomocysteinase | 0.1216 | 1 | 1 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0085 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1015 | 0.096 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0753 | 0.6024 | 0.6024 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.1216 | 1 | 1 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.1216 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.1216 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.1216 | 1 | 1 |
Treponema pallidum | adenosine deaminase | 0.0085 | 0.0299 | 0.5 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.1216 | 1 | 1 |
Brugia malayi | hypoxia-induced factor 1 | 0.0155 | 0.0903 | 0.0903 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.1216 | 1 | 1 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.1216 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.1216 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0169 | 0.1015 | 0.1015 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0753 | 0.6024 | 0.6024 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0753 | 0.6024 | 0.6024 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0085 | 0.0299 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
BP (functional) | NA 0 mmHg | Antihypertensive activity in spontaneously hypertensive rats, measured as average blood pressure at 100 mg/kg,po before predose; No significant lowering of blood pressure | ChEMBL. | 7452694 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.