Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | macroglobulin/complement | 0.0051 | 0.3355 | 1 |
Loa Loa (eye worm) | A-macroglobulin complement component family protein | 0.0051 | 0.3355 | 1 |
Echinococcus multilocularis | alpha 2 macroglobulin | 0.0051 | 0.3355 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.2597 | 0.7741 |
Echinococcus multilocularis | cd109 antigen | 0.0048 | 0.2597 | 0.7741 |
Echinococcus granulosus | cd109 antigen | 0.0048 | 0.2597 | 1 |
Brugia malayi | A-macroglobulin complement component family protein | 0.0051 | 0.3355 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI (functional) | = 0 % | Growth inhibition of Mycobacterium tuberculosis H37Rv at 6.25 ug/mL by microplate alamar blue assay | ChEMBL. | 17561405 |
GI (functional) | = 0 % | Growth inhibition of Mycobacterium tuberculosis H37Rv at 6.25 ug/mL by microplate alamar blue assay | ChEMBL. | 17561405 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.