Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0042 | 1 | 1 |
Leishmania major | sodium/sulphate symporter, putative | 0.0005 | 0.0489 | 0.0489 |
Giardia lamblia | Kinase, CMGC CDK | 0.0042 | 1 | 1 |
Trypanosoma brucei | CYC2-like cyclin, putative | 0.0025 | 0.5771 | 0.5771 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0042 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0042 | 1 | 1 |
Echinococcus multilocularis | xenotropic and polytropic retrovirus receptor 1 | 0.0005 | 0.0489 | 0.0489 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0042 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase | 0.0042 | 1 | 1 |
Toxoplasma gondii | SPX domain-containing protein | 0.0005 | 0.0489 | 0.0489 |
Giardia lamblia | Xenotropic and polytropic murine leukemia virus receptor | 0.0005 | 0.0489 | 0.0489 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0042 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.5771 | 0.5771 |
Plasmodium falciparum | protein kinase 5 | 0.0042 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0042 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0042 | 1 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0042 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0042 | 1 | 1 |
Toxoplasma gondii | cyclin2 related protein | 0.0025 | 0.5771 | 0.5771 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0042 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0042 | 1 | 1 |
Trypanosoma brucei | cyclin 2 | 0.0025 | 0.5771 | 0.5771 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0042 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0042 | 1 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.0025 | 0.5771 | 0.5771 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0042 | 1 | 1 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0042 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.9886 | 0.988 |
Toxoplasma gondii | vacuolar transporter chaperone VTC2 | 0.0005 | 0.0489 | 0.0489 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0042 | 1 | 1 |
Leishmania major | CYC2-like cyclin, putative | 0.0025 | 0.5771 | 0.5771 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 1 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0042 | 1 | 1 |
Echinococcus granulosus | xenotropic and polytropic retrovirus receptor 1 | 0.0005 | 0.0489 | 0.0489 |
Schistosoma mansoni | xenotropic and polytropic murine leukemia virus receptor xpr1 | 0.0005 | 0.0489 | 0.0489 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0042 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0042 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0042 | 1 | 1 |
Trypanosoma cruzi | CYC2-like cyclin 4, putative | 0.0025 | 0.5771 | 0.5771 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 1 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0042 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0042 | 1 | 1 |
Trypanosoma cruzi | Low-affinity phosphate transporter PHO91 | 0.0005 | 0.0489 | 0.0489 |
Trypanosoma cruzi | CYC2-like cyclin 6, putative | 0.0025 | 0.5771 | 0.5771 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0042 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 1 | 1 |
Toxoplasma gondii | cyclin, N-terminal domain-containing protein | 0.0025 | 0.5771 | 0.5771 |
Giardia lamblia | Kinase, CMGC CDK | 0.0042 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0005 | 0.0489 | 0.0489 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.