Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | ryanodine receptor | 0.0636 | 0.13 | 0.224 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.2182 | 0.7833 | 1 |
Echinococcus granulosus | ryanodine receptor 44f | 0.2182 | 0.7833 | 1 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.1702 | 0.5805 | 0.725 |
Loa Loa (eye worm) | hypothetical protein | 0.1702 | 0.5805 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0491 | 0.069 | 0.1189 |
Leishmania major | hypothetical protein, conserved | 0.066 | 0.1404 | 0.5 |
Echinococcus granulosus | ryanodine receptor 44f | 0.1702 | 0.5805 | 0.725 |
Schistosoma mansoni | ryanodine receptor related | 0.2694 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0513 | 0.078 | 0.1344 |
Schistosoma mansoni | hypothetical protein | 0.0664 | 0.1421 | 0.1421 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0806 | 0.2021 | 0.2021 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0971 | 0.2719 | 0.5 |
Loa Loa (eye worm) | ryanodine receptor | 0.1006 | 0.2867 | 0.4938 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0806 | 0.2021 | 0.2121 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0971 | 0.2719 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0806 | 0.2021 | 0.2121 |
Schistosoma mansoni | inositol 145-trisphosphate receptor | 0.0824 | 0.2094 | 0.2094 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 17197178 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.