Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Echinococcus multilocularis | a disintegrin and metalloproteinase with | Get druggable targets OG5_126771 | All targets in OG5_126771 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | Get druggable targets OG5_126771 | All targets in OG5_126771 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_126771 | All targets in OG5_126771 |
Brugia malayi | ADAM-TS Spacer 1 family protein | Get druggable targets OG5_126771 | All targets in OG5_126771 |
Schistosoma japonicum | ko:K08624 ADAM metallopeptidase with thrombospondin type 1 motif, 9, putative | Get druggable targets OG5_126771 | All targets in OG5_126771 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | Get druggable targets OG5_126771 | All targets in OG5_126771 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0046 | 0.0086 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.1441 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.1441 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.1441 | 1 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.1441 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0539 | 1 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0046 | 0.0086 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.055 | 0.3668 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.055 | 0.3668 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.055 | 0.3668 | 0.5 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.055 | 0.3668 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.055 | 0.3668 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.055 | 0.3668 | 0.5 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0046 | 0.0086 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.1441 | 1 | 0.5 |
Brugia malayi | ADAM-TS Spacer 1 family protein | 0.0109 | 0.0539 | 1 |
Treponema pallidum | polypeptide deformylase (def) | 0.1441 | 1 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.1441 | 1 | 0.5 |
Onchocerca volvulus | Papilin homolog | 0.0035 | 0.0007 | 0.5 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.055 | 0.3668 | 0.5 |
Plasmodium falciparum | peptide deformylase | 0.1441 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.