Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.3078 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0908 | 0.2535 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0908 | 0.2535 | 0.5 |
Trypanosoma brucei | lipase domain protein, putative | 0.0908 | 0.2535 | 1 |
Mycobacterium tuberculosis | Probable amidase AmiB2 (aminohydrolase) | 0.0371 | 0.0688 | 1 |
Mycobacterium tuberculosis | Possible amidase (aminohydrolase) | 0.0371 | 0.0688 | 1 |
Mycobacterium ulcerans | peptide amidase, GatA | 0.0371 | 0.0688 | 1 |
Mycobacterium ulcerans | amidase | 0.0371 | 0.0688 | 1 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0371 | 0.0688 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0908 | 0.2535 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.3078 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0371 | 0.0688 | 0.5 |
Mycobacterium tuberculosis | Probable amidase AmiD (acylamidase) (acylase) | 0.0371 | 0.0688 | 1 |
Mycobacterium ulcerans | amidase | 0.0371 | 0.0688 | 1 |
Loa Loa (eye worm) | lipase | 0.0908 | 0.2535 | 0.1984 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.0908 | 0.2535 | 0.1984 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0371 | 0.0688 | 0.5 |
Mycobacterium ulcerans | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0371 | 0.0688 | 1 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.0908 | 0.2535 | 0.1984 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0371 | 0.0688 | 0.5 |
Mycobacterium ulcerans | amidase | 0.0371 | 0.0688 | 1 |
Trichomonas vaginalis | lipase containing protein, putative | 0.0908 | 0.2535 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.3078 | 1 | 1 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0371 | 0.0688 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0908 | 0.2535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3078 | 1 | 1 |
Mycobacterium tuberculosis | Probable amidase AmiA2 (aminohydrolase) | 0.0371 | 0.0688 | 1 |
Brugia malayi | Lipase family protein | 0.0908 | 0.2535 | 0.1984 |
Schistosoma mansoni | amidase | 0.3078 | 1 | 1 |
Mycobacterium tuberculosis | Probable amidase AmiC (aminohydrolase) | 0.0371 | 0.0688 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.3078 | 1 | 1 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0371 | 0.0688 | 0.5 |
Mycobacterium ulcerans | amidase | 0.0371 | 0.0688 | 1 |
Onchocerca volvulus | 0.0908 | 0.2535 | 0.5 | |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.3078 | 1 | 1 |
Trypanosoma brucei | lipase domain protein, putative | 0.0908 | 0.2535 | 1 |
Mycobacterium ulcerans | amidase | 0.0371 | 0.0688 | 1 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0371 | 0.0688 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 10.2 uM | DPPH radical scavenging activity | ChEMBL. | 17602526 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.