Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Metabotropic glutamate receptor 5 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0047 | 0.0758 | 1 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0324 | 1 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0047 | 0.0758 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0047 | 0.0758 | 1 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0324 | 1 | 0.5 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0047 | 0.0758 | 0.7326 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0047 | 0.0758 | 1 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0047 | 0.0758 | 0.2129 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0758 | 0.2129 |
Echinococcus granulosus | aminopeptidase N | 0.0131 | 0.3559 | 1 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0047 | 0.0758 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1979 | 0.7067 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0041 | 0.0546 | 0.5276 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Brugia malayi | Peptidase family M1 containing protein | 0.0047 | 0.0758 | 0.2129 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0044 | 0.0657 | 0.1846 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0109 | 0.2801 | 1 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0056 | 0.1034 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1188 | 0.424 |
Loa Loa (eye worm) | glutamate receptor | 0.0049 | 0.0811 | 0.2894 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Entamoeba histolytica | aminopeptidase, putative | 0.0047 | 0.0758 | 0.5 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0324 | 1 | 1 |
Echinococcus multilocularis | aminopeptidase N | 0.0131 | 0.3559 | 1 |
Toxoplasma gondii | aminopeptidase N protein | 0.0324 | 1 | 0.5 |
Onchocerca volvulus | 0.0131 | 0.3559 | 1 | |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0047 | 0.0758 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.006 | 0.1188 | 0.3337 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0041 | 0.0546 | 0.1533 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0047 | 0.0758 | 1 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0047 | 0.0758 | 1 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0049 | 0.0811 | 0.2278 |
Brugia malayi | Peptidase family M1 containing protein | 0.0131 | 0.3559 | 1 |
Onchocerca volvulus | 0.0047 | 0.0758 | 0.2129 | |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0047 | 0.0758 | 1 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.006 | 0.1188 | 0.3337 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0047 | 0.0758 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.2737 | 0.9772 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0047 | 0.0758 | 1 |
Loa Loa (eye worm) | aminopeptidase N | 0.0047 | 0.0758 | 0.2705 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0047 | 0.0758 | 0.7326 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0047 | 0.0758 | 0.2129 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0041 | 0.0546 | 0.1533 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.