Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | kinesin family member 11 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | leucine-rich repeat protein (LRRP), putative | 0.0001 | 0 | 0.5 |
Brugia malayi | Kinesin motor domain containing protein | 0.0032 | 0.1262 | 1 |
Trichomonas vaginalis | chaoptin, putative | 0.0001 | 0 | 0.5 |
Trichomonas vaginalis | toll, putative | 0.0001 | 0 | 0.5 |
Giardia lamblia | Kinesin-5 | 0.0032 | 0.1262 | 0.5 |
Schistosoma mansoni | kinesin eg-5 | 0.0032 | 0.1262 | 0.1451 |
Onchocerca volvulus | 0.0046 | 0.1805 | 0.5 | |
Trypanosoma cruzi | protein phosphatase 1, regulatory subunit, putative | 0.0001 | 0 | 0.5 |
Trichomonas vaginalis | leucine-rich repeat containing protein, putative | 0.0001 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0001 | 0 | 0.5 |
Echinococcus multilocularis | kinesin family 1 | 0.0247 | 1 | 1 |
Plasmodium vivax | kinesin-5 | 0.0032 | 0.1262 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0.8695 | 1 |
Trypanosoma cruzi | protein phosphatase 1, regulatory subunit, putative | 0.0001 | 0 | 0.5 |
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0032 | 0.1262 | 1 |
Entamoeba histolytica | kinesin, putative | 0.0032 | 0.1262 | 1 |
Trichomonas vaginalis | leucine-rich transmembrane protein, putative | 0.0001 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0001 | 0 | 0.5 |
Plasmodium falciparum | kinesin-5 | 0.0032 | 0.1262 | 0.5 |
Trypanosoma brucei | protein phosphatase 1, regulatory subunit, putative | 0.0001 | 0 | 0.5 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0032 | 0.1262 | 0.5 |
Trichomonas vaginalis | leucine-rich repeat-containing protein, putative | 0.0001 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.