Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.812 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0301 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.6487 | 0.346 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.812 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.812 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.7313 | 0.9956 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.7313 | 0.9956 |
Treponema pallidum | hypothetical protein | 0.004 | 0.0089 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0089 | 0.5 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0231 | 0.7346 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0251 | 0.812 | 0.8054 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.812 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.7313 | 0.4998 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.7346 | 0.5058 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0165 | 0.4831 | 0.4648 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0231 | 0.7346 | 1 |
Trypanosoma cruzi | ferric reductase transmembrane protein, putative | 0.0141 | 0.3926 | 0.5 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.7075 | 0.5 |
Brugia malayi | hypothetical protein | 0.023 | 0.7313 | 0.7218 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.812 | 1 |
Leishmania major | ferric reductase, putative | 0.0141 | 0.3926 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.812 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0251 | 0.812 | 0.65 |
Trypanosoma brucei | ferric reductase transmembrane protein, putative | 0.0141 | 0.3926 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.5169 | 0.1027 |
Trypanosoma cruzi | ferric reductase transmembrane protein, putative | 0.0141 | 0.3926 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.5169 | 0.1027 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0231 | 0.7346 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0301 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.