Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | gamma-secretase subunit aph-1 | 0.9484 | 1 | 1 |
Echinococcus granulosus | presenilin | 0.0443 | 0.0308 | 0.0245 |
Brugia malayi | hypothetical protein | 0.0216 | 0.0065 | 0.0065 |
Trichomonas vaginalis | Clan AD, family A22, presenilin-like aspartic peptidase | 0.0443 | 0.0308 | 1 |
Loa Loa (eye worm) | gamma-secretase subunit pen-2 | 0.0415 | 0.0279 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0065 | 0.0065 |
Entamoeba histolytica | presenilin 1 peptidase, putative | 0.0443 | 0.0308 | 0.5 |
Trichomonas vaginalis | Clan AD, family A22, presenilin-like aspartic peptidase | 0.0443 | 0.0308 | 1 |
Echinococcus multilocularis | presenilin | 0.0443 | 0.0308 | 0.0245 |
Trypanosoma brucei | Aph-1 protein, putative | 0.3696 | 0.3795 | 1 |
Brugia malayi | Presenilin family protein | 0.0443 | 0.0308 | 0.0308 |
Schistosoma mansoni | subfamily A22A unassigned peptidase (A22 family) | 0.0443 | 0.0308 | 0.0245 |
Echinococcus multilocularis | presenilin enhancer 2 | 0.0415 | 0.0279 | 0.0215 |
Toxoplasma gondii | hypothetical protein | 0.0155 | 0 | 0.5 |
Loa Loa (eye worm) | gamma-secretase subunit aph-1 | 0.9484 | 1 | 1 |
Leishmania major | presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative | 0.0443 | 0.0308 | 0.5 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.3696 | 0.3795 | 1 |
Brugia malayi | gamma-secretase subunit pen-2 | 0.0415 | 0.0279 | 0.0279 |
Brugia malayi | hypothetical protein | 0.0216 | 0.0065 | 0.0065 |
Echinococcus multilocularis | gamma secretase subunit aph 1 | 0.9484 | 1 | 1 |
Echinococcus granulosus | presenilin enhancer 2 | 0.0415 | 0.0279 | 0.0215 |
Trichomonas vaginalis | Clan AD, family A22, presenilin-like aspartic peptidase | 0.0443 | 0.0308 | 1 |
Echinococcus granulosus | gamma secretase subunit aph 1 | 0.9484 | 1 | 1 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.3696 | 0.3795 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.