Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | membrane bound transcription factor site 1 | 0.0167 | 1 | 0.5 |
Onchocerca volvulus | 0.0167 | 1 | 0.5 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.114 | 0.114 |
Echinococcus multilocularis | membrane bound transcription factor site 1 | 0.0167 | 1 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.114 | 0.114 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.114 | 0.114 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 1 | 1 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.0167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.114 | 0.114 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 425 uM | Inhibition of rabbit muscle GPa | ChEMBL. | 17719791 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.