Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0043 | 0.0535 | 0.0531 |
Echinococcus granulosus | glutamate receptor 2 | 0.0043 | 0.0535 | 0.0531 |
Loa Loa (eye worm) | glutamate receptor | 0.0179 | 0.3027 | 0.3027 |
Loa Loa (eye worm) | hypothetical protein | 0.0561 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0043 | 0.0535 | 0.0531 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0456 | 0.8077 | 1 |
Echinococcus multilocularis | tyrosine kinase | 0.0043 | 0.0535 | 0.0531 |
Loa Loa (eye worm) | intermediate filament protein | 0.0014 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | glutamate receptor | 0.0456 | 0.8077 | 0.8077 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0043 | 0.0535 | 0.0531 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0074 | 0.1104 | 0.11 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0043 | 0.0535 | 0.0531 |
Leishmania major | extracellular receptor, putative | 0.0043 | 0.0535 | 0.5 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0535 | 0.0658 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1104 | 0.1104 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0222 | 0.381 | 0.4131 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0043 | 0.0535 | 0.0531 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0043 | 0.0535 | 0.0531 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0043 | 0.0535 | 0.0531 |
Echinococcus granulosus | glutamate receptor 2 | 0.0043 | 0.0535 | 0.0531 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0043 | 0.0535 | 0.0535 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0043 | 0.0535 | 0.0531 |
Onchocerca volvulus | 0.0043 | 0.0535 | 0.4829 | |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0382 | 0.6726 | 0.6724 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0382 | 0.6726 | 0.7295 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Schistosoma mansoni | tyrosine kinase | 0.0043 | 0.0535 | 0.0576 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0117 | 0.1886 | 0.1886 |
Schistosoma mansoni | protein kinase | 0.0043 | 0.0535 | 0.0576 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0043 | 0.0535 | 0.0531 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0074 | 0.1104 | 0.1362 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0222 | 0.381 | 0.4714 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.1104 | 0.1193 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0519 | 0.9217 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0535 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0043 | 0.0535 | 0.0576 |
Trypanosoma cruzi | extracellular receptor, putative | 0.0043 | 0.0535 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0043 | 0.0535 | 0.0531 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0382 | 0.6726 | 0.6724 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0043 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0117 | 0.1886 | 0.1886 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0074 | 0.1104 | 0.11 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0535 | 0.0535 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0043 | 0.0535 | 0.4829 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0043 | 0.0535 | 0.0531 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0074 | 0.1104 | 1 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0117 | 0.1886 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0005 | 0.0005 |
Schistosoma mansoni | tyrosine kinase | 0.0043 | 0.0535 | 0.0576 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0043 | 0.0535 | 0.0531 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0043 | 0.0535 | 0.0531 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0413 | 0.7294 | 0.903 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0043 | 0.0535 | 0.0658 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0043 | 0.0535 | 0.0535 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0561 | 1 | 1 |
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0074 | 0.1104 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0043 | 0.0535 | 0.0531 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0043 | 0.0535 | 0.0658 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0043 | 0.0535 | 0.0658 |
Echinococcus granulosus | tyrosine kinase | 0.0043 | 0.0535 | 0.0531 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0043 | 0.0535 | 0.0531 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0043 | 0.0535 | 0.0531 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.1886 | 0.1886 |
Onchocerca volvulus | 0.0043 | 0.0535 | 0.4829 | |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0043 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0014 | 0.0005 | 0.0005 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.