Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | MAP kinase activated protein kinase 2 | 0.3647 | 1 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0235 | 0.0058 | 1 |
Loa Loa (eye worm) | STE/STE7/MEK1 protein kinase | 0.0235 | 0.0058 | 0.0058 |
Leishmania major | mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 | 0.0235 | 0.0058 | 1 |
Echinococcus multilocularis | dual specificity mitogen activated protein | 0.0235 | 0.0058 | 0.0058 |
Echinococcus granulosus | dual specificity mitogen activated protein | 0.0235 | 0.0058 | 0.0058 |
Trichomonas vaginalis | STE family protein kinase | 0.0235 | 0.0058 | 1 |
Brugia malayi | Dual specificity mitogen-activated protein kinase kinase mek-2 | 0.0235 | 0.0058 | 0.0058 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0215 | 0 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0235 | 0.0058 | 1 |
Loa Loa (eye worm) | camk/mapkapk/mapkapk protein kinase | 0.3647 | 1 | 1 |
Trypanosoma brucei | mitogen-activated protein kinase kinase 5 | 0.0235 | 0.0058 | 1 |
Giardia lamblia | Kinase, STE STE20 | 0.0235 | 0.0058 | 1 |
Echinococcus granulosus | MAP kinase activated protein kinase 2 | 0.3647 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase kinase 5 | 0.0235 | 0.0058 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.3647 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0235 | 0.0058 | 0.0058 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.