Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.1766 | 0.3612 | 0.3658 |
Loa Loa (eye worm) | hypothetical protein | 0.2345 | 0.4945 | 0.5329 |
Plasmodium falciparum | carbonic anhydrase | 0.1766 | 0.3612 | 0.5 |
Leishmania major | carbonic anhydrase family protein, putative | 0.3391 | 0.7358 | 0.7935 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.1724 | 0.3515 | 0.5311 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.4197 | 0.9217 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1766 | 0.3612 | 0.3871 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.4197 | 0.9217 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1766 | 0.3612 | 0.3871 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.3391 | 0.7358 | 1 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.4197 | 0.9217 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1766 | 0.3612 | 0.3871 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1766 | 0.3612 | 0.3658 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1766 | 0.3612 | 0.3658 |
Echinococcus multilocularis | carbonic anhydrase II | 0.4197 | 0.9217 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.4537 | 1 | 0.5 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.4197 | 0.9217 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.4197 | 0.9217 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.4197 | 0.9217 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.3391 | 0.7358 | 0.7897 |
Echinococcus multilocularis | carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Echinococcus granulosus | carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.4197 | 0.9217 | 0.5 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.3391 | 0.7358 | 0.5 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.4197 | 0.9217 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1766 | 0.3612 | 0.3871 |
Leishmania major | carbonic anhydrase-like protein | 0.4197 | 0.9217 | 1 |
Onchocerca volvulus | 0.02 | 0 | 0.5 | |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.3043 | 0.6556 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1766 | 0.3612 | 0.3871 |
Onchocerca volvulus | Putative sulfate transporter | 0.02 | 0 | 0.5 |
Schistosoma mansoni | carbonic anhydrase | 0.1766 | 0.3612 | 0.3658 |
Echinococcus granulosus | geminin | 0.0364 | 0.038 | 0.0336 |
Echinococcus granulosus | carbonic anhydrase II | 0.4197 | 0.9217 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1766 | 0.3612 | 0.3871 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1766 | 0.3612 | 0.3658 |
Echinococcus granulosus | carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.4197 | 0.9217 | 1 |
Toxoplasma gondii | hypothetical protein | 0.1766 | 0.3612 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.1897 | 0.3914 | 0.5926 |
Echinococcus multilocularis | geminin | 0.0364 | 0.038 | 0.0336 |
Echinococcus granulosus | carbonic anhydrase | 0.1766 | 0.3612 | 0.3871 |
Trichomonas vaginalis | conserved hypothetical protein | 0.4537 | 1 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1766 | 0.3612 | 0.3871 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.