Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Ribosomal protein L34a | 0.0129 | 0.6438 | 0.6438 |
Toxoplasma gondii | hypothetical protein | 0.0046 | 0 | 0.5 |
Echinococcus multilocularis | Ribosomal protein L34a | 0.0129 | 0.6438 | 0.6438 |
Schistosoma mansoni | beta-14-galactosyltransferase | 0.0174 | 1 | 1 |
Echinococcus granulosus | Metazoa galactosyltransferase | 0.0174 | 1 | 1 |
Schistosoma mansoni | beta-14-galactosyltransferase | 0.0174 | 1 | 1 |
Echinococcus multilocularis | Metazoa galactosyltransferase | 0.0174 | 1 | 1 |
Loa Loa (eye worm) | galactosyltransferase | 0.0174 | 1 | 1 |
Echinococcus multilocularis | Metazoa galactosyltransferase | 0.0147 | 0.7898 | 0.7898 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 25922 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Streptococcus faecalis ATCC 29212 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 32 ug ml-1 | Antifungal activity against Aspergillus niger NCIM 590 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 32 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 25922 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against Bacillus subtilis ATCC 6033 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 64 ug ml-1 | Antifungal activity against Aspergillus flavus NCIM 539 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 64 ug ml-1 | Antifungal activity against Candida albicans NCIM C27 by serial dilution method | ChEMBL. | 17942305 |
MIC (functional) | = 64 ug ml-1 | Antifungal activity against Candida albicans NCIM C27 by serial dilution method | ChEMBL. | 17942305 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.