Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0527 | 0.0877 | 1 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0527 | 0.0877 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0774 | 0.2227 | 1 |
Brugia malayi | hypothetical protein | 0.1051 | 0.3744 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0527 | 0.0877 | 0.0818 |
Echinococcus multilocularis | dual specificity | 0.0774 | 0.2227 | 0.2176 |
Loa Loa (eye worm) | hypothetical protein | 0.0762 | 0.2162 | 0.2162 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0378 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0527 | 0.0877 | 0.0877 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0774 | 0.2227 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0527 | 0.0877 | 0.3757 |
Loa Loa (eye worm) | hypothetical protein | 0.0762 | 0.2162 | 0.2162 |
Echinococcus granulosus | hypothetical protein | 0.0515 | 0.0812 | 0.0752 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0774 | 0.2227 | 0.2176 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0774 | 0.2227 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0527 | 0.0877 | 0.2208 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0378 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0378 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.2196 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0774 | 0.2227 | 0.5877 |
Entamoeba histolytica | protein kinase, putative | 0.0774 | 0.2227 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0774 | 0.2227 | 1 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0527 | 0.0877 | 0.3757 |
Giardia lamblia | Kinase, CMGC CLK | 0.0527 | 0.0877 | 1 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.2196 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0527 | 0.0877 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0527 | 0.0877 | 0.3757 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0527 | 0.0877 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1051 | 0.3744 | 0.3744 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0527 | 0.0877 | 0.0818 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0527 | 0.0877 | 0.3757 |
Echinococcus multilocularis | 0.0515 | 0.0812 | 0.0752 | |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0774 | 0.2227 | 0.2227 |
Leishmania major | protein kinase, putative | 0.0527 | 0.0877 | 0.3757 |
Loa Loa (eye worm) | hypothetical protein | 0.0515 | 0.0812 | 0.0812 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0527 | 0.0877 | 0.3757 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0774 | 0.2227 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0774 | 0.2227 | 1 |
Echinococcus granulosus | dual specificity | 0.0774 | 0.2227 | 0.2176 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0774 | 0.2227 | 1 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0527 | 0.0877 | 0.3757 |
Loa Loa (eye worm) | hypothetical protein | 0.1051 | 0.3744 | 0.3744 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.2196 | 1 | 1 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0527 | 0.0877 | 0.0818 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0527 | 0.0877 | 0.0818 |
Leishmania major | protein kinase, putative | 0.0527 | 0.0877 | 0.3757 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.