Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Staphylococcus aureus subsp. aureus Mu50 | Peptide deformylase | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Trichomonas vaginalis | abca6, putative | Peptide deformylase | 183 aa | 162 aa | 25.3 % |
Trypanosoma cruzi | hypothetical protein | Peptide deformylase | 183 aa | 155 aa | 22.6 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.1199 | 0.5198 |
Brugia malayi | hypothetical protein | 0.0126 | 0.1199 | 0.5198 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.2293 | 1 |
Onchocerca volvulus | 0.0244 | 0.2661 | 1 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0014 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.1199 | 0.5198 |
Mycobacterium ulcerans | peptide deformylase | 0.0279 | 0.3095 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0014 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0279 | 0.3095 | 0.5 |
Chlamydia trachomatis | peptide deformylase | 0.0279 | 0.3095 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0279 | 0.3095 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0106 | 0.0954 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.0279 | 0.3095 | 1 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0106 | 0.0954 | 0.5 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0106 | 0.0954 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0014 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0279 | 0.3095 | 1 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0106 | 0.0954 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.2293 | 1 |
Plasmodium falciparum | peptide deformylase | 0.0279 | 0.3095 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0106 | 0.0954 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0106 | 0.0954 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0244 | 0.2661 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0126 | 0.1199 | 0.4476 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0014 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0106 | 0.0954 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.0279 | 0.3095 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0126 | 0.1199 | 0.4476 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0279 | 0.3095 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.