Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0098 | 0.1209 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0358 | 0.0358 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0159 | 0.2031 | 0.2343 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0098 | 0.1209 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0358 | 0.5 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0098 | 0.1209 | 0.1209 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0156 | 0.1988 | 0.1988 |
Schistosoma mansoni | hypothetical protein | 0.0203 | 0.2625 | 0.2625 |
Echinococcus multilocularis | 0.0098 | 0.1209 | 0.1209 | |
Onchocerca volvulus | 0.0098 | 0.1209 | 1 | |
Brugia malayi | hypothetical protein | 0.0098 | 0.1209 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0358 | 0.2959 |
Plasmodium vivax | hypothetical protein, conserved | 0.0098 | 0.1209 | 0.5 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0098 | 0.1209 | 0.5 |
Echinococcus granulosus | geminin | 0.0203 | 0.2625 | 0.3028 |
Brugia malayi | SWIRM domain containing protein | 0.0098 | 0.1209 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0358 | 0.0358 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0098 | 0.1209 | 0.5 |
Schistosoma mansoni | amine oxidase | 0.0098 | 0.1209 | 0.1209 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1209 | 1 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0098 | 0.1209 | 0.1395 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0098 | 0.1209 | 0.1209 |
Schistosoma mansoni | amine oxidase | 0.0098 | 0.1209 | 0.1209 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1209 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1209 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0098 | 0.1209 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1209 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0358 | 0.5 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0747 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0098 | 0.1209 | 0.5 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0098 | 0.1209 | 0.5 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0747 | 1 | 1 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0098 | 0.1209 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1209 | 1 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0098 | 0.1209 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0358 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1209 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0358 | 0.0358 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0159 | 0.2031 | 0.2031 |
Leishmania major | UDP-galactopyranose mutase | 0.0098 | 0.1209 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0358 | 0.5 |
Mycobacterium tuberculosis | Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) | 0.0648 | 0.8668 | 1 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0098 | 0.1209 | 0.5 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0098 | 0.1209 | 0.5 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0098 | 0.1209 | 0.1395 |
Echinococcus granulosus | ankyrin repeat protein | 0.0156 | 0.1988 | 0.2293 |
Schistosoma mansoni | hypothetical protein | 0.0203 | 0.2625 | 0.2625 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0358 | 0.5 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0156 | 0.1988 | 0.1988 |
Echinococcus granulosus | protoporphyrinogen oxidase | 0.0648 | 0.8668 | 1 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0747 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0747 | 1 | 0.5 |
Echinococcus multilocularis | geminin | 0.0203 | 0.2625 | 0.2625 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.