Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.1018 | 1 | 1 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.0841 | 0.8124 | 0.8105 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma cruzi | nucleoside transporter-like, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma cruzi | nucleoside transporter-like, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2, putative | 0.0177 | 0.1074 | 1 |
Leishmania major | inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 | 0.0177 | 0.1074 | 1 |
Brugia malayi | hypothetical protein | 0.0177 | 0.1074 | 0.0981 |
Leishmania major | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Toxoplasma gondii | nucleoside transporter protein | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | unspecified product | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2, putative | 0.0177 | 0.1074 | 1 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.1018 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0177 | 0.1074 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1018 | 1 | 1 |
Leishmania major | nucleobase transporter | 0.0177 | 0.1074 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1018 | 1 | 1 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.1018 | 1 | 1 |
Trypanosoma cruzi | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Schistosoma mansoni | equilibrative nucleoside transporter | 0.0177 | 0.1074 | 1 |
Trypanosoma cruzi | nucleobase transporter, putative | 0.0177 | 0.1074 | 1 |
Toxoplasma gondii | nucleoside transporter protein | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1 | 0.0177 | 0.1074 | 1 |
Trypanosoma cruzi | nucleobase transporter, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | purine nucleoside transporter | 0.0177 | 0.1074 | 1 |
Echinococcus multilocularis | equilibrative nucleoside transporter 3 | 0.1018 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.1018 | 1 | 0.5 |
Trypanosoma brucei | adenosine transporter, putative | 0.0177 | 0.1074 | 1 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.1018 | 1 | 1 |
Trypanosoma cruzi | nucleobase transporter, putative | 0.0177 | 0.1074 | 1 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.1018 | 1 | 1 |
Leishmania major | nucleobase transporter | 0.0177 | 0.1074 | 1 |
Entamoeba histolytica | nucleoside transporter, putative | 0.1018 | 1 | 1 |
Trypanosoma cruzi | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2 | 0.0177 | 0.1074 | 1 |
Trypanosoma cruzi | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1074 | 0.0981 |
Brugia malayi | hypothetical protein | 0.1018 | 1 | 1 |
Trypanosoma brucei | adenosine transporter, putative | 0.0177 | 0.1074 | 1 |
Toxoplasma gondii | nucleoside transporter protein | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2, putative | 0.0177 | 0.1074 | 1 |
Echinococcus granulosus | equilibrative nucleoside transporter 3 | 0.1018 | 1 | 1 |
Trypanosoma brucei | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | unspecified product | 0.0177 | 0.1074 | 1 |
Trichomonas vaginalis | equilibrative nucleoside transporter, putative | 0.1018 | 1 | 1 |
Echinococcus granulosus | equilibrative nucleoside transporter | 0.1018 | 1 | 1 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1 | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | nucleobase/nucleoside transporter 8.1, putative | 0.0177 | 0.1074 | 1 |
Onchocerca volvulus | Equilibrative nucleoside transporter, putative homolog | 0.1018 | 1 | 1 |
Trypanosoma brucei | purine nucleoside transporter | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Trypanosoma brucei | adenosine transporter 2 | 0.0177 | 0.1074 | 1 |
Echinococcus multilocularis | equilibrative nucleoside transporter protein | 0.1018 | 1 | 1 |
Leishmania major | nucleoside transporter 1, putative | 0.0177 | 0.1074 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
pKB (binding) | = 5.5 | Binding affinity for Cholecystokinin type A receptor in Guinea-Pig gall bladder | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.