Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0.0064 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4722 | 0.4688 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.7379 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4722 | 0.4688 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4439 | 0.4403 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.8876 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.7379 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.4439 | 0.5381 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.7379 | 0.7362 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.4439 | 0.5396 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0.0064 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.1014 | 0.0453 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0191 | 0.0127 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0003 | 0 | 0.5 |
Onchocerca volvulus | 0.003 | 0.4439 | 0.5 | |
Trypanosoma brucei | ISWI complex protein | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0004 | 0.0082 | 0.1363 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.7379 | 0.7362 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0711 | 0.0651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.7379 | 0.7362 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.7379 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.4722 | 0.6015 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.4722 | 0.6015 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.1014 | 0.0453 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 0.41 | Agonist activity human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase relative to NECA | ChEMBL. | 18321038 |
Activity (functional) | = 0.41 | Agonist activity human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase relative to NECA | ChEMBL. | 18321038 |
logEC50 (functional) | = -1.736 | Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase | ChEMBL. | 18321038 |
logEC50 (functional) | = -1.736 | Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclase | ChEMBL. | 18321038 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.