Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0413 | 0.5126 | 0.3566 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2606 | 0.0238 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0413 | 0.5126 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2606 | 0.0238 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0413 | 0.5126 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2606 | 0.0238 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0607 | 1 | 1 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0413 | 0.5126 | 0.5 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0413 | 0.5126 | 0.5 |
Toxoplasma gondii | peptidase family M13 protein | 0.0413 | 0.5126 | 0.5 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0413 | 0.5126 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0413 | 0.5126 | 0.3566 |
Loa Loa (eye worm) | hypothetical protein | 0.0413 | 0.5126 | 0.3566 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2606 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2606 | 0.0238 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0413 | 0.5126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.2606 | 0.0238 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | 0 | Anti-invasive activity against human PC3M cells at 50 nM | ChEMBL. | 18222089 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.