Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor X | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | t-complex protein beta subunit | 0.0026 | 1 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.4297 | 0.5 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0026 | 1 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 1 | 1 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0026 | 1 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.4297 | 0.4297 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0026 | 1 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.4297 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.4297 | 0.5 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 1 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.4297 | 0.5 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0026 | 1 | 1 |
Onchocerca volvulus | Arrow homolog | 0.0016 | 0 | 0.5 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0026 | 1 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.4297 | 0.4297 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 1 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.4297 | 0.4297 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0026 | 1 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.4297 | 0.4297 |
Trichomonas vaginalis | chaperonin, putative | 0.0026 | 1 | 1 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.4297 | 0.4297 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.4297 | 0.4297 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.4297 | 0.4297 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0026 | 1 | 1 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0026 | 1 | 1 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0026 | 1 | 1 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0026 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.