Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Plasmodium falciparum | casein kinase 2, alpha subunit | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.009 | 0.3294 | 0.3294 |
Toxoplasma gondii | CMGC kinase, CK2 family | 0.0079 | 0.2476 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Entamoeba histolytica | casein kinase, putative | 0.0079 | 0.2476 | 1 |
Echinococcus granulosus | casein kinase ii subunit alpha | 0.0079 | 0.2476 | 0.7516 |
Loa Loa (eye worm) | CMGC/CK2 protein kinase | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | transfer RNA-Trp | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Trypanosoma cruzi | casein kinase II, putative | 0.0079 | 0.2476 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.009 | 0.3294 | 0.3294 |
Leishmania major | casein kinase II, putative | 0.0079 | 0.2476 | 1 |
Schistosoma mansoni | hypothetical protein | 0.009 | 0.3294 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0079 | 0.2476 | 1 |
Echinococcus granulosus | 5'partial|3'partial|non capsid protein NS 1 | 0.009 | 0.3294 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Onchocerca volvulus | Casein kinase II subunit beta homolog | 0.0043 | 0 | 0.5 |
Echinococcus multilocularis | casein kinase ii subunit alpha | 0.0079 | 0.2476 | 0.2476 |
Trypanosoma brucei | Casein kinase II | 0.0079 | 0.2476 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0079 | 0.2476 | 1 |
Onchocerca volvulus | Casein kinase II subunit beta homolog | 0.0043 | 0 | 0.5 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.009 | 0.3294 | 0.3294 |
Giardia lamblia | Kinase, CMGC CK2 | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.009 | 0.3294 | 0.3294 |
Plasmodium vivax | casein kinase 2, alpha subunit, putative | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0079 | 0.2476 | 0.7516 |
Echinococcus multilocularis | non capsid protein NS 1 | 0.0187 | 1 | 1 |
Brugia malayi | Casein kinase II, alpha chain | 0.0079 | 0.2476 | 1 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0187 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 27.1 mg kg-1 | Analgesic activity in sc dosed mouse by hot-plate method | ChEMBL. | 209187 |
Log 1/C (functional) | = 1.08 | Analgesic activity assayed with the mouse hot-plate method | ChEMBL. | 7057419 |
Log 1/C (functional) | = 1.08 | Analgesic activity assayed with the mouse hot-plate method | ChEMBL. | 7057419 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.