Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | cdc25b, putative | 0.0057 | 0.399 | 0.5 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0057 | 0.399 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0026 | 0.0461 | 0.0575 |
Onchocerca volvulus | 0.0057 | 0.399 | 0.5 | |
Trichomonas vaginalis | cdc25c, putative | 0.0057 | 0.399 | 0.5 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.0057 | 0.399 | 0.4981 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.399 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0026 | 0.0461 | 0.0575 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0026 | 0.0461 | 0.0575 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0026 | 0.0461 | 0.0575 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0057 | 0.399 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.3489 | 0.8744 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0057 | 0.399 | 0.5 |
Trichomonas vaginalis | cdc25b, putative | 0.0057 | 0.399 | 0.5 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0057 | 0.399 | 0.5 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0026 | 0.0461 | 0.0575 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0085 | 0.7112 | 0.8879 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0026 | 0.0461 | 0.0575 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.0057 | 0.399 | 0.5 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.0057 | 0.399 | 0.4981 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.399 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0093 | 0.801 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0026 | 0.0461 | 0.0575 |
Echinococcus granulosus | glutamate receptor 2 | 0.0026 | 0.0461 | 0.0575 |
Onchocerca volvulus | 0.0057 | 0.399 | 0.5 | |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0057 | 0.399 | 0.5 |
Schistosoma mansoni | m-phase inducer phosphatase(cdc25) | 0.0057 | 0.399 | 0.399 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0026 | 0.0461 | 0.0575 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.0057 | 0.399 | 0.5 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0026 | 0.0461 | 0.0575 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0089 | 0.7572 | 0.9453 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0085 | 0.7112 | 0.8879 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0089 | 0.7572 | 0.9453 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0093 | 0.801 | 1 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0057 | 0.399 | 0.5 |
Onchocerca volvulus | 0.0057 | 0.399 | 0.5 | |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.0057 | 0.399 | 0.5 |
Brugia malayi | Rhodanese-like domain containing protein | 0.0057 | 0.399 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.3489 | 0.8744 |
Onchocerca volvulus | 0.0057 | 0.399 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.