Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lamin | 0.0027 | 0.3331 | 0.3331 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0477 | 0.1432 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.3331 | 1 |
Onchocerca volvulus | 0.0027 | 0.3331 | 1 | |
Schistosoma mansoni | lamin | 0.0027 | 0.3331 | 0.3331 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0575 | 0.0575 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 1 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 1 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 1 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0857 | 0.2574 |
Onchocerca volvulus | 0.0027 | 0.3331 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0477 | 0.1432 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.3331 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0575 | 0.0575 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 1 | 0.5 |
Echinococcus multilocularis | musashi | 0.0027 | 0.3331 | 0.3331 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.3331 | 0.3331 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.3331 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0857 | 0.2574 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.3331 | 0.3331 |
Schistosoma mansoni | lamin | 0.0027 | 0.3331 | 0.3331 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.3331 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 1 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.3331 | 0.3331 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0575 | 0.1725 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.3331 | 0.3331 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.3331 | 1 |
Echinococcus granulosus | lamin | 0.0027 | 0.3331 | 0.3331 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.3234 | 0.9707 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.