Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.0133 | 0.022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0133 | 0.022 |
Onchocerca volvulus | Glutaminyl cyclase homolog | 0.0225 | 0.6039 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0191 | 0.4866 | 0.4797 |
Echinococcus multilocularis | tumor protein p63 | 0.034 | 1 | 1 |
Onchocerca volvulus | 0.011 | 0.2091 | 0.3463 | |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0191 | 0.4866 | 0.8057 |
Schistosoma mansoni | hypothetical protein | 0.0199 | 0.513 | 0.8494 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0133 | 0.022 |
Echinococcus granulosus | glutaminyl peptide cyclotransferase | 0.0225 | 0.6039 | 0.5986 |
Schistosoma mansoni | alpha-glucosidase | 0.0164 | 0.395 | 0.654 |
Schistosoma mansoni | glutaminyl cyclase (M28 family) | 0.0225 | 0.6039 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0164 | 0.395 | 0.654 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0191 | 0.4866 | 0.4797 |
Schistosoma mansoni | hypothetical protein | 0.0199 | 0.513 | 0.8494 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0191 | 0.4866 | 0.4797 |
Echinococcus granulosus | geminin | 0.0199 | 0.513 | 0.5064 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0191 | 0.4866 | 0.8014 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.6039 | 1 |
Echinococcus multilocularis | glutaminyl peptide cyclotransferase | 0.0225 | 0.6039 | 0.5986 |
Echinococcus multilocularis | geminin | 0.0199 | 0.513 | 0.5064 |
Brugia malayi | Peptidase family M28 containing protein | 0.0225 | 0.6039 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0133 | 0.022 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.