Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.3739 | 0.8198 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0577 | 0.5 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0577 | 0.1306 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.3739 | 0.8462 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0577 | 0.1306 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0577 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0577 | 0.5 |
Echinococcus granulosus | jun protein | 0.0082 | 0.4561 | 0.4561 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0577 | 0.0577 |
Brugia malayi | RNA binding protein | 0.0069 | 0.3739 | 0.8198 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0577 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0577 | 0.0577 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0577 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0577 | 0.0577 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0577 | 0.0577 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0577 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 0.5 |
Brugia malayi | bZIP transcription factor family protein | 0.0082 | 0.4561 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0577 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0577 | 0.0577 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0577 | 0.0577 |
Brugia malayi | hypothetical protein | 0.0065 | 0.3445 | 0.7554 |
Schistosoma mansoni | jun-related protein | 0.0067 | 0.3587 | 0.3587 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0577 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0577 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3739 | 0.3739 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.3739 | 0.8462 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0082 | 0.4561 | 0.4561 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0577 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.4418 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0577 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0577 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0577 | 0.5 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0577 | 0.0577 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0577 | 0.1265 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3739 | 0.3739 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.3739 | 0.3739 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.3739 | 0.8198 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0082 | 0.4561 | 0.4561 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0577 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0577 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0577 | 0.1265 |
Echinococcus multilocularis | geminin | 0.0169 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3739 | 0.3739 |
Echinococcus multilocularis | jun protein | 0.0082 | 0.4561 | 0.4561 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.3739 | 0.3739 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3739 | 0.3739 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.3587 | 0.3587 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0577 | 0.0577 |
Onchocerca volvulus | 0.0065 | 0.3445 | 1 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0577 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.3739 | 0.8462 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3739 | 0.3739 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0577 | 0.0577 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0577 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.