Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0071 | 0.3668 | 1 | |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0046 | 0.0162 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2961 | 0.2961 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0015 | 0.0046 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0046 | 0.0162 |
Echinococcus multilocularis | phd:f box containing protein | 0.0015 | 0.0046 | 0.0046 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0046 | 0.0162 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0046 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0046 | 0.0162 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2961 | 0.2961 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0058 | 0.2838 | 0.2838 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.2961 | 0.2961 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0015 | 0.0046 | 0.0046 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0015 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0046 | 0.0162 |
Echinococcus multilocularis | geminin | 0.0167 | 1 | 1 |
Schistosoma mansoni | protein phosphatase 2C | 0.0015 | 0.0046 | 0.0046 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0046 | 0.0126 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0058 | 0.2838 | 0.2838 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0015 | 0.0046 | 0.0156 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.2838 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.2838 | 1 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0056 | 0.2699 | 1 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0015 | 0.0046 | 0.0046 |
Schistosoma mansoni | jumonji domain containing protein | 0.0015 | 0.0046 | 0.0046 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0056 | 0.2699 | 0.7358 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0058 | 0.2838 | 0.2838 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.2961 | 0.2961 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2961 | 1 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0056 | 0.2699 | 1 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0015 | 0.0046 | 0.0046 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Leishmania major | fatty-acid desaturase, putative | 0.0071 | 0.3668 | 1 |
Schistosoma mansoni | phd/f-box containing protein | 0.0015 | 0.0046 | 0.0046 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0046 | 0.0126 |
Onchocerca volvulus | 0.0071 | 0.3668 | 1 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2961 | 1 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.0071 | 0.3668 | 1 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0015 | 0.0046 | 0.0046 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.2961 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.2838 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0071 | 0.3668 | 1 |
Echinococcus granulosus | phd:f box containing protein | 0.0015 | 0.0046 | 0.0046 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0015 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0046 | 0.0162 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0015 | 0.0046 | 0.0126 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0015 | 0.0046 | 0.0046 |
Brugia malayi | acyl-CoA desaturase | 0.0056 | 0.2699 | 0.951 |
Schistosoma mansoni | jumonji domain containing protein | 0.0058 | 0.2838 | 0.2838 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.0056 | 0.2699 | 0.951 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0015 | 0.0046 | 0.0046 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0058 | 0.2838 | 0.2838 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0046 | 0.0126 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0046 | 0.0162 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.2838 | 0.2838 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2961 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.2961 | 0.8074 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.2961 | 1 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0015 | 0.0046 | 0.0046 |
Leishmania major | stearic acid desaturase, putative | 0.0071 | 0.3668 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.2838 | 0.2838 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0046 | 0.0162 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0056 | 0.2699 | 0.7358 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0046 | 0.0162 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0015 | 0.0046 | 0.0046 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
9 literature references were collected for this gene.