Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | STE/STE20 serine/threonine-protein kinase, putative | 0.0502 | 0.242 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0878 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.087 | 0.9851 | 1 |
Trypanosoma cruzi | p21-activated kinase 3, putative | 0.0502 | 0.242 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0878 | 1 | 1 |
Trichomonas vaginalis | mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative | 0.0502 | 0.242 | 0.242 |
Trichomonas vaginalis | STE family protein kinase | 0.0878 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0878 | 1 | 1 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0878 | 1 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0878 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0502 | 0.242 | 0.242 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0502 | 0.242 | 0.242 |
Giardia lamblia | Kinase, STE STE20 | 0.0878 | 1 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0878 | 1 | 1 |
Loa Loa (eye worm) | STE/STE20/PAKB protein kinase | 0.0567 | 0.3724 | 0.1755 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0878 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0878 | 1 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0878 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0878 | 1 | 1 |
Entamoeba histolytica | p21-activated kinase | 0.0878 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.087 | 0.9851 | 0.9851 |
Brugia malayi | serine/threonine-protein kinase PAK 7 | 0.0567 | 0.3724 | 0.172 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0878 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0878 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.