Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | neuropeptide receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | nAChR subunit | 0.0079 | 0.1055 | 0.2915 |
Echinococcus granulosus | g-protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0079 | 0.1055 | 0.3098 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0171 | 0.3152 | 1 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1055 | 0.1413 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | carboxylesterase 5A | 0.0071 | 0.0873 | 0.25 |
Brugia malayi | ORL1-like opioid receptor | 0.0094 | 0.1395 | 0.1924 |
Echinococcus multilocularis | sex peptide receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | Cation transporter family protein | 0.0171 | 0.3152 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0092 | 0.1356 | 0.3934 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | neuropeptide receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0094 | 0.1395 | 0.4218 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0083 | 0.1149 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Echinococcus granulosus | allatostatin A receptor | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | neuropeptide receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0171 | 0.3152 | 0.4092 |
Echinococcus granulosus | fmrfamide receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0171 | 0.3152 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0873 | 0.0873 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0171 | 0.3152 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | sulfakinin receptor protein | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | myosin xvIII | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | neuropeptide s receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0171 | 0.3152 | 0.3152 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Brugia malayi | Neuronal acetylcholine receptor protein, alpha-2 chain precursor | 0.0079 | 0.1055 | 0.1413 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0171 | 0.3152 | 1 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0171 | 0.3152 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0094 | 0.1395 | 0.1924 |
Echinococcus granulosus | serotonin receptor | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | neuronal acetylcholine receptor protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.4981 | 0.4981 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0071 | 0.0873 | 0.2301 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Schistosoma mansoni | neuropeptide receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0303 | 0.6182 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | neuropeptide receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0171 | 0.3152 | 0.4561 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0094 | 0.1395 | 0.0664 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0171 | 0.3152 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0094 | 0.1395 | 0.1924 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Brugia malayi | Melatonin receptor type 1A | 0.0094 | 0.1395 | 0.1924 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0171 | 0.3152 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | serotonin receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0873 | 0.0873 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | g protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | acetylcholinesterase | 0.0071 | 0.0873 | 0.25 |
Brugia malayi | neuropeptide F receptor | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0171 | 0.3152 | 0.4561 |
Schistosoma mansoni | opsin-like receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0071 | 0.0873 | 0.25 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0092 | 0.1356 | 0.1865 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0171 | 0.3152 | 0.4561 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0079 | 0.1055 | 0.2915 |
Brugia malayi | Carboxylesterase family protein | 0.0071 | 0.0873 | 0.114 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1055 | 0.1413 |
Echinococcus multilocularis | neuropeptide receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0092 | 0.1356 | 0.1865 |
Brugia malayi | Dopamine receptor protein 2 | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0037 | 0.0113 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Echinococcus granulosus | g protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0171 | 0.3152 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0079 | 0.1055 | 0.3098 |
Brugia malayi | G-protein coupled receptor | 0.0094 | 0.1395 | 0.1924 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0079 | 0.1055 | 0.2915 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0171 | 0.3152 | 0.4561 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0092 | 0.1356 | 0.1356 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0171 | 0.3152 | 1 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Brugia malayi | AKH receptor | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0171 | 0.3152 | 0.3152 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | nAChR subunit | 0.0079 | 0.1055 | 0.2915 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0171 | 0.3152 | 0.4561 |
Echinococcus granulosus | nAChR subunit | 0.0092 | 0.1356 | 0.409 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Giardia lamblia | Telomerase catalytic subunit | 0.0083 | 0.1149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | g protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0083 | 0.1149 | 0.5 |
Brugia malayi | Acetylcholine receptor protein, alpha-like chain 1 precursor | 0.0079 | 0.1055 | 0.1413 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0083 | 0.1149 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0094 | 0.1395 | 0.4065 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0057 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus multilocularis | acetylcholinesterase | 0.0071 | 0.0873 | 0.25 |
Echinococcus multilocularis | somatostatin receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0094 | 0.1395 | 0.4218 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0256 | 0.5102 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0092 | 0.1356 | 0.5 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0094 | 0.1395 | 0.4065 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | g protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0079 | 0.1055 | 0.2915 |
Brugia malayi | larval opioid receptor | 0.0094 | 0.1395 | 0.1924 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0171 | 0.3152 | 0.3152 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0079 | 0.1055 | 0.2915 |
Onchocerca volvulus | 0.0171 | 0.3152 | 0.4092 | |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0083 | 0.1149 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0092 | 0.1356 | 0.3934 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | Serotonin receptor | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | G-protein coupled receptor | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | biogenic amine receptor | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0079 | 0.1055 | 0.1413 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1055 | 0.1413 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | nAChR subunit | 0.0092 | 0.1356 | 0.409 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Schistosoma mansoni | amine GPCR | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0171 | 0.3152 | 0.4561 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | g protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | GnHR receptor homolog | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Onchocerca volvulus | 0.0171 | 0.3152 | 0.4092 | |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0171 | 0.3152 | 0.3152 |
Onchocerca volvulus | 0.0171 | 0.3152 | 0.4092 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0171 | 0.3152 | 0.3152 |
Brugia malayi | Dopamine receptor | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0171 | 0.3152 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | Cation transporter family protein | 0.0171 | 0.3152 | 0.4561 |
Echinococcus multilocularis | fmrfamide receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0092 | 0.1356 | 0.1865 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0094 | 0.1395 | 0.1924 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0079 | 0.1055 | 0.3098 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | Serotonin receptor | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus granulosus | nAChR subunit | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 0.6778 | 0.6778 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1055 | 0.1413 |
Schistosoma mansoni | neuropeptide receptor | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | neuropeptide F receptor | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0171 | 0.3152 | 0.4561 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.033 | 0.6778 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0171 | 0.3152 | 0.4561 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | acetylcholinesterase | 0.0071 | 0.0873 | 0.25 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0079 | 0.1055 | 0.1413 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0079 | 0.1055 | 0.1055 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0171 | 0.3152 | 0.4561 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0079 | 0.1055 | 0.3098 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | histamine h1 receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0171 | 0.3152 | 1 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1055 | 0.1413 |
Schistosoma mansoni | amine GPCR | 0.0094 | 0.1395 | 0.4065 |
Onchocerca volvulus | 0.0171 | 0.3152 | 0.4092 | |
Brugia malayi | Carboxylesterase family protein | 0.0071 | 0.0873 | 0.114 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0171 | 0.3152 | 0.4561 |
Onchocerca volvulus | 0.0171 | 0.3152 | 0.4092 | |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | amine GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0171 | 0.3152 | 0.3152 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0171 | 0.3152 | 0.4561 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0092 | 0.1356 | 0.3934 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | carboxylesterase | 0.0071 | 0.0873 | 0.0873 |
Brugia malayi | Cation transporter family protein | 0.0171 | 0.3152 | 0.4561 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0094 | 0.1395 | 0.4065 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0079 | 0.1055 | 0.1413 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0083 | 0.1149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0094 | 0.1395 | 0.0664 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | amine GPCR | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0171 | 0.3152 | 0.4561 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Schistosoma mansoni | amine GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | serotonin receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0171 | 0.3152 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0071 | 0.0873 | 0.0873 |
Loa Loa (eye worm) | LGC-31 protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus multilocularis | acetylcholinesterase | 0.0071 | 0.0873 | 0.25 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | acetylcholine receptor protein | 0.0079 | 0.1055 | 0.1055 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Brugia malayi | hypothetical protein | 0.0094 | 0.1395 | 0.1924 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | biogenic amine receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.3152 | 0.3152 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | RE15519p | 0.0094 | 0.1395 | 0.1924 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0083 | 0.1149 | 0.5 |
Loa Loa (eye worm) | ACC-1 protein | 0.0171 | 0.3152 | 0.3152 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0094 | 0.1395 | 0.1924 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.1356 | 0.1356 |
Schistosoma mansoni | opsin-like receptor | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | biogenic amine receptor | 0.0094 | 0.1395 | 0.4065 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0171 | 0.3152 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0094 | 0.1395 | 0.4065 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | g protein coupled receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | hypothetical protein | 0.0094 | 0.1395 | 0.4218 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Echinococcus multilocularis | allatostatin A receptor | 0.0094 | 0.1395 | 0.4218 |
Onchocerca volvulus | 0.0092 | 0.1356 | 0.0588 | |
Echinococcus granulosus | glycine receptor subunit beta | 0.0171 | 0.3152 | 1 |
Onchocerca volvulus | 0.0171 | 0.3152 | 0.4092 | |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Brugia malayi | putative neuropeptide receptor | 0.0094 | 0.1395 | 0.1924 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0171 | 0.3152 | 0.4561 |
Schistosoma mansoni | nAChR subunit | 0.0171 | 0.3152 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0094 | 0.1395 | 0.4218 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0094 | 0.1395 | 0.1924 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1055 | 0.1055 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.1395 | 0.4065 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Brugia malayi | follicle stimulating hormone receptor | 0.0094 | 0.1395 | 0.1924 |
Onchocerca volvulus | 0.0092 | 0.1356 | 0.0588 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0094 | 0.1395 | 0.4218 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0171 | 0.3152 | 0.3152 |
Brugia malayi | Telomerase reverse transcriptase | 0.0221 | 0.4291 | 0.6268 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0092 | 0.1356 | 0.1865 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0094 | 0.1395 | 0.4065 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0079 | 0.1055 | 0.1413 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0171 | 0.3152 | 0.4561 |
Onchocerca volvulus | 0.0094 | 0.1395 | 0.0664 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0094 | 0.1395 | 0.4218 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0171 | 0.3152 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | nAChR subunit | 0.0171 | 0.3152 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0094 | 0.1395 | 0.1924 |
Echinococcus granulosus | sex peptide receptor | 0.0094 | 0.1395 | 0.4218 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0057 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1395 | 0.1395 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0171 | 0.3152 | 1 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0079 | 0.1055 | 0.3098 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 42 mg kg-1 | Anticonvulsant activity of the compound, 0.5 h after administration of compound in mice subjected to subcutaneous metrazole challenge (85 mg/kg) | ChEMBL. | 2544727 |
ED50 (functional) | = 42 mg kg-1 | Anticonvulsant activity of the compound, 0.5 h after administration of compound in mice subjected to subcutaneous metrazole challenge (85 mg/kg) | ChEMBL. | 2544727 |
ED50 (functional) | = 141 mg kg-1 | Anticonvulsant activity of the compound, 0.5 h after administration in maximal electroshock mice model | ChEMBL. | 2544727 |
ED50 (functional) | = 141 mg kg-1 | Anticonvulsant activity of the compound, 0.5 h after administration in maximal electroshock mice model | ChEMBL. | 2544727 |
Inhibition (binding) | = 36 % | Displacement of [3H]-BTX-B from rat cerebral cortex voltage-gated sodium channel, 0.5 hr after 500 uM | ChEMBL. | 2544727 |
Inhibition (binding) | = 36 % | Displacement of [3H]-BTX-B from rat cerebral cortex voltage-gated sodium channel, 0.5 hr after 500 uM | ChEMBL. | 2544727 |
TD50 (ADMET) | = 155 mg kg-1 | Anticonvulsant activity of the compound,0.5 h after administration in mice subjected to rotorod toxicity test | ChEMBL. | 2544727 |
TD50 (ADMET) | = 155 mg kg-1 | Anticonvulsant activity of the compound,0.5 h after administration in mice subjected to rotorod toxicity test | ChEMBL. | 2544727 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.