Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0018 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0018 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0018 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Plasmodium vivax | aldehyde reductase, putative | 0.0018 | 1 | 0.5 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Entamoeba histolytica | aldose reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0018 | 1 | 0.5 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Echinococcus granulosus | hypothetical protein | 0.0018 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0018 | 1 | 0.5 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0018 | 1 | 0.5 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0018 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0018 | 1 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0018 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0018 | 1 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0018 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0018 | 1 | 0.5 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0018 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0018 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0018 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0018 | 1 | 0.5 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0018 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0018 | 1 | 0.5 |
Toxoplasma gondii | aldo-keto reductase | 0.0018 | 1 | 0.5 |
Schistosoma mansoni | pol-related | 0.0018 | 1 | 1 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0018 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0018 | 1 | 1 |
Mycobacterium leprae | Possible oxidoreductase | 0.0018 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0018 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0018 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0018 | 1 | 0.5 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Echinococcus multilocularis | aldo keto reductase | 0.0018 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0018 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0018 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0018 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0018 | 1 | 1 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0018 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Onchocerca volvulus | 0.0018 | 1 | 1 | |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0018 | 1 | 1 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0018 | 1 | 0.5 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0018 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0018 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0018 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0018 | 1 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Leishmania major | prostaglandin f synthase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0018 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0018 | 1 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0018 | 1 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0018 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0018 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.