Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0206 | 0.1447 | 1 | |
Toxoplasma gondii | hypothetical protein | 0.0314 | 0.2358 | 1 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0702 | 0.5607 | 1 |
Brugia malayi | plexin A | 0.0047 | 0.0117 | 0.0109 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.0508 | 0.3983 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0314 | 0.2358 | 0.4146 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0702 | 0.5607 | 1 |
Loa Loa (eye worm) | plexin A | 0.0047 | 0.0117 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.2358 | 0.4146 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0314 | 0.2358 | 0.4146 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0314 | 0.2358 | 0.4146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1227 | 1 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase | 0.0314 | 0.2358 | 0.4082 |
Echinococcus multilocularis | carbonic anhydrase | 0.0314 | 0.2358 | 0.4082 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0314 | 0.2358 | 0.4146 |
Onchocerca volvulus | Putative sulfate transporter | 0.0206 | 0.1447 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0314 | 0.2358 | 0.4146 |
Echinococcus granulosus | carbonic anhydrase | 0.0314 | 0.2358 | 0.4082 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.0979 | 0.7923 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0314 | 0.2358 | 0.4146 |
Plasmodium falciparum | carbonic anhydrase | 0.0314 | 0.2358 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0702 | 0.5607 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0702 | 0.5607 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0702 | 0.5607 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1227 | 1 | 0.5 |
Leishmania major | carbonic anhydrase-like protein | 0.0702 | 0.5607 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0702 | 0.5607 | 1 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0702 | 0.5607 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.0314 | 0.2358 | 0.4146 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.2358 | 0.4146 |
Schistosoma mansoni | carbonic anhydrase | 0.0508 | 0.3983 | 0.7074 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.2358 | 0.4146 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0702 | 0.5607 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0314 | 0.2358 | 0.4146 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.0508 | 0.3983 | 0.5 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0702 | 0.5607 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0314 | 0.2358 | 0.4146 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0702 | 0.5607 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0314 | 0.2358 | 0.4146 |
Chlamydia trachomatis | sulfate transporter | 0.0033 | 0 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0314 | 0.2358 | 0.4146 |
Echinococcus granulosus | carbonic anhydrase | 0.0314 | 0.2358 | 0.4082 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0485 | 0.379 | 0.3344 |
Plasmodium vivax | sulfate transporter, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | carbonic anhydrase | 0.0314 | 0.2358 | 0.4082 |
Echinococcus granulosus | carbonic anhydrase II | 0.0702 | 0.5607 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0314 | 0.2358 | 0.4082 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.026 | 0.1906 | 0.031 |
Mycobacterium ulcerans | carbonic anhydrase | 0.0508 | 0.3983 | 0.3983 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.