Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | musashi | 0.0026 | 1 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.8593 | 0.5 |
Echinococcus multilocularis | lamin | 0.0026 | 1 | 0.5 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.8593 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.8593 | 0.8593 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.8593 | 0.5 |
Onchocerca volvulus | 0.0026 | 1 | 0.5 | |
Onchocerca volvulus | 0.0026 | 1 | 0.5 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.8593 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 1 | 1 |
Echinococcus granulosus | lamin | 0.0026 | 1 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.9606 | 0.9606 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 1 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 1 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.8593 | 0.5 |
Brugia malayi | hypothetical protein | 0.0025 | 0.8593 | 0.8593 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.1458 | 0.1458 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.8593 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.8593 | 0.5 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.8593 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.