TDR Targets

Basic information

Technical information

TDR Targets ID: 619871
Name: ethyl 2-[[5-[(4-morpholin-4-ylsulfonylbenzoyl )amino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetat e
MW: 472.559 | Formula: C17H20N4O6S3
H donors: 1 H acceptors: 6 LogP: 1.44 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: CCOC(=O)CSc1nnc(s1)NC(=O)c1ccc(cc1)S(=O)(=O)N1CCOCC1
InChi: 1S/C17H20N4O6S3/c1-2-27-14(22)11-28-17-20-19-16(29-17)18-15(23)12-3-5-13(6-4-12)30(24,25)21-7-9-26-10-8-21/h3-6H,2,7-11H2,1H3,(H,18,19,23)
InChiKey: LPJSRJSTHXFVCG-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

ethyl 2-[[5-[(4-morpholinosulfonylbenzoyl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]acetate
2-[[5-[[(4-morpholinosulfonylphenyl)-oxomethyl]amino]-1,3,4-thiadiazol-2-yl]thio]acetic acid ethyl ester
2-[[5-[(4-morpholinosulfonylbenzoyl)amino]-1,3,4-thiadiazol-2-yl]thio]acetic acid ethyl ester
ethyl 2-[[5-[(4-morpholin-4-ylsulfonylphenyl)carbonylamino]-1,3,4-thiadiazol-2-yl]sulfanyl]ethanoate
Oprea1_771119

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	transcription factor LCR-F1	0.0037	0.0585	0.2722
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.0032	0.0457	0.1855
Plasmodium falciparum	proline--tRNA ligase	0.0037	0.0577	0.051
Onchocerca volvulus		0.0015	0.0071	1
Brugia malayi	lysyl-tRNA synthetase	0.0024	0.0271	0.126
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0033	0.0481	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Echinococcus granulosus	GPCR family 2	0.0016	0.009	0.042
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0472	0.2194
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0032	0.0472	0.0404
Entamoeba histolytica	hypothetical protein	0.0037	0.0585	1
Trypanosoma brucei	glucose transporter 2A	0.0033	0.0481	0.8107
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0024	0.0271	0.0961
Entamoeba histolytica	hypothetical protein	0.0037	0.0585	1
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Trichomonas vaginalis	sugar transporter, putative	0.0033	0.0481	0.1973
Chlamydia trachomatis	lysine--tRNA ligase	0.0024	0.0271	0.5
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0032	0.0472	0.0617
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0037	0.0585	0.2722
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0032	0.0472	0.0617
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.0032	0.0457	0.2124
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0032	0.0457	0.2124
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0071	0.0331
Trypanosoma cruzi	hexose transporter	0.0033	0.0481	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0032	0.0472	0.2194
Schistosoma mansoni	glucose transport protein	0.0105	0.215	1
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0037	0.0577	1
Trypanosoma cruzi	hexose transporter, putative	0.0018	0.0141	0.1383
Brugia malayi	Sugar transporter family protein	0.0105	0.215	1
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.017	0.3641	0.5495
Schistosoma mansoni	hypothetical protein	0.0105	0.215	1
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0016	0.009	0.042
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0507	0.2359
Schistosoma mansoni	protein kinase	0.0032	0.0472	0.2194
Schistosoma mansoni	hypothetical protein	0.0034	0.0507	0.2359
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0037	0.0577	1
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0032	0.0472	0.2194
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0032	0.0457	0.2124
Brugia malayi	Cam kinase protein 1	0.0032	0.0472	0.2194
Schistosoma mansoni	lysyl-tRNA synthetase	0.0024	0.0271	0.126
Onchocerca volvulus	Putative transporter	0.0015	0.0071	1
Onchocerca volvulus		0.0015	0.0071	1
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Onchocerca volvulus		0.0015	0.0071	1
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0024	0.0271	0.395
Trichomonas vaginalis	conserved hypothetical protein	0.0105	0.215	1
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0024	0.0271	0.3046
Trypanosoma cruzi	hexose transporter, putative	0.0033	0.0481	0.8107
Schistosoma mansoni	sugar transporter	0.0015	0.0071	0.0331
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0033	0.0481	0.8107
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.0032	0.0457	0.2124
Leishmania major	glucose transporter, lmgt3	0.0033	0.0481	0.8107
Schistosoma mansoni	hypothetical protein	0.0016	0.009	0.042
Trichomonas vaginalis	sugar transporter, putative	0.0033	0.0481	0.1973
Schistosoma mansoni	glucose transport protein	0.0105	0.215	1
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Plasmodium falciparum	protein kinase 7	0.0298	0.6567	0.6542
Trypanosoma cruzi	hexose transporter, putative	0.0033	0.0481	0.8107
Schistosoma mansoni	hypothetical protein	0.0016	0.009	0.042
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Entamoeba histolytica	hypothetical protein	0.0037	0.0585	1
Trypanosoma cruzi	hexose transporter, putative	0.0033	0.0481	0.8107
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0015	0.0071	0.0331
Leishmania major	protein kinase, putative	0.0032	0.0472	0.7919
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0016	0.009	0.042
Toxoplasma gondii	lysine-tRNA ligase	0.0024	0.0271	0.0308
Echinococcus granulosus	General substrate transporter	0.0091	0.181	0.8418
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.009	0.042
Schistosoma mansoni	hypothetical protein	0.0016	0.009	0.042
Schistosoma mansoni	sugar transporter	0.0015	0.0071	0.0331
Entamoeba histolytica	hypothetical protein	0.0037	0.0585	1
Leishmania major	glucose transporter, lmgt2	0.0033	0.0481	0.8107
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0037	0.0577	0.0779
Onchocerca volvulus		0.0015	0.0071	1
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Plasmodium falciparum	hexose transporter	0.0105	0.215	0.2094
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0457	0.2124
Brugia malayi	Sugar transporter family protein	0.0015	0.0071	0.0331
Plasmodium falciparum	mitogen-activated protein kinase 2	0.017	0.3641	0.3595
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0867	0.4031
Brugia malayi	hypothetical protein	0.0015	0.0071	0.0331
Onchocerca volvulus		0.0015	0.0071	1
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Brugia malayi	hypothetical protein	0.0037	0.0585	0.2722
Schistosoma mansoni	glucose transport protein	0.0105	0.215	1
Toxoplasma gondii	protein kinase, putative	0.0298	0.6567	1
Schistosoma mansoni	hypothetical protein	0.0037	0.0585	0.2722
Loa Loa (eye worm)	sugar transporter	0.0105	0.215	1
Brugia malayi	hypothetical protein	0.0015	0.0071	0.0331
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0021	0.0204	0.0641
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0015	0.0071	0.0331
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.0032	0.0457	1
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0481	0.1973
Loa Loa (eye worm)	hypothetical protein	0.0016	0.009	0.042
Onchocerca volvulus		0.0015	0.0071	1
Giardia lamblia	Lysyl-tRNA synthetase	0.0024	0.0271	0.5182
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.0032	0.0457	0.2124
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0015	0.0071	0.0331
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0013	0.0029	0.0134
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0024	0.0271	1
Plasmodium vivax	proline--tRNA ligase, putative	0.0037	0.0577	0.051
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0032	0.0472	0.0404
Onchocerca volvulus		0.0015	0.0071	1
Echinococcus granulosus	solute carrier family 22	0.0015	0.0071	0.0331
Trichomonas vaginalis	glucose transporter, putative	0.0033	0.0481	0.1973
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.002	0.019	1
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0016	0.009	0.042
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Brugia malayi	hypothetical protein	0.0015	0.0071	0.0331
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0015	0.0071	0.5
Echinococcus multilocularis	calcium dependent protein kinase	0.003	0.0426	0.1981
Entamoeba histolytica	protein kinase, putative	0.0032	0.0472	0.6385
Entamoeba histolytica	protein kinase, putative	0.0032	0.0472	0.6385
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0032	0.0472	0.0617
Plasmodium vivax	hexose transporter	0.0105	0.215	0.2094
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.0032	0.0457	0.5908
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0016	0.009	0.042
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.009	0.042
Echinococcus multilocularis	lysyl tRNA synthetase	0.0024	0.0271	0.126
Trichomonas vaginalis	sugar transporter, putative	0.0033	0.0481	0.1973
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0037	0.0585	0.2722
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0032	0.0472	0.7919
Brugia malayi	Major Facilitator Superfamily protein	0.0015	0.0071	0.0331
Onchocerca volvulus		0.0015	0.0071	1
Echinococcus granulosus	synaptic vesicle 2 protein	0.0015	0.0071	0.0331
Brugia malayi	Major Facilitator Superfamily protein	0.0015	0.0071	0.0331
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.002	0.019	1
Schistosoma mansoni	sugar transporter	0.0015	0.0071	0.0331
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Onchocerca volvulus		0.0015	0.0071	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0507	0.2359
Schistosoma mansoni	serine/threonine protein kinase	0.0032	0.0472	0.2194
Echinococcus granulosus	lysyl tRNA synthetase	0.0024	0.0271	0.126
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0867	0.4031
Plasmodium falciparum	lysine--tRNA ligase	0.0024	0.0271	0.0201
Schistosoma mansoni	protein kinase	0.0032	0.0472	0.2194
Trichomonas vaginalis	CAMK family protein kinase	0.0032	0.0472	0.1927
Echinococcus granulosus	solute carrier family 22	0.0015	0.0071	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0867	0.4031
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0024	0.0271	1
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.0032	0.0457	0.2124
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0071	0.0331
Onchocerca volvulus		0.0015	0.0071	1
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0032	0.0472	0.0404
Schistosoma mansoni	lysyl-tRNA synthetase	0.0024	0.0271	0.126
Onchocerca volvulus		0.0015	0.0071	1
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0032	0.0472	0.0404
Giardia lamblia	Prolyl-tRNA synthetase	0.0032	0.0457	1
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0032	0.0472	0.0404
Onchocerca volvulus		0.0015	0.0071	1
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0032	0.0472	0.2194
Loa Loa (eye worm)	sugar transporter	0.0015	0.0071	0.0331
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0032	0.0472	0.0404
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0015	0.0071	0.0331
Echinococcus multilocularis	GPCR, family 2	0.0016	0.009	0.042
Toxoplasma gondii	facilitative glucose transporter GT1	0.0105	0.215	0.3201
Leishmania major	lysyl-tRNA synthetase, putative	0.0024	0.0271	0.395
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0457	0.2124
Onchocerca volvulus		0.0015	0.0071	1
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0015	0.0071	0.0331
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0071	0.0331
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0037	0.0577	1
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0032	0.0472	0.2194
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0032	0.0472	0.2194
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0032	0.0472	0.0404
Leishmania major	glucose transporter, lmgt1	0.0033	0.0481	0.8107
Trichomonas vaginalis	glucose transporter, putative	0.0033	0.0481	0.1973
Onchocerca volvulus		0.0015	0.0071	1
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0015	0.0071	0.0331
Plasmodium vivax	lysine--tRNA ligase, putative	0.0024	0.0271	0.0201
Echinococcus multilocularis	solute carrier family 22	0.0015	0.0071	0.0331
Trypanosoma brucei	glucose transporter 1E	0.0033	0.0481	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.017	0.3641	0.3595
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Onchocerca volvulus		0.0015	0.0071	1
Brugia malayi	Sugar transporter family protein	0.0015	0.0071	0.0331
Schistosoma mansoni	hypothetical protein	0.0016	0.009	0.042
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0016	0.009	0.042
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0271	0.126
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0033	0.0481	0.8107
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0321	0.1491
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0024	0.0271	0.395
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0032	0.0472	0.0404
Echinococcus granulosus	calcium dependent protein kinase	0.003	0.0426	0.1981
Echinococcus granulosus	solute carrier family 22	0.0015	0.0071	0.0331
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0037	0.0577	1
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0071	0.0331
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0105	0.215	1
Brugia malayi	Major Facilitator Superfamily protein	0.0015	0.0071	0.0331
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0037	0.0577	1
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0032	0.0472	0.0404
Echinococcus multilocularis	General substrate transporter	0.0091	0.181	0.8418
Schistosoma mansoni	sugar transporter	0.0015	0.0071	0.0331
Trypanosoma brucei	glucose transporter, putative	0.0033	0.0481	0.8107
Brugia malayi	major facilitator superfamily protein	0.0015	0.0071	0.0331
Onchocerca volvulus		0.0015	0.0071	1
Schistosoma mansoni	protein kinase	0.0032	0.0472	0.2194
Plasmodium vivax	CDK-related protein kinase 6, putative	0.0447	1	1
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0867	0.4031
Echinococcus granulosus	solute carrier family 22	0.0015	0.0071	0.0331
Schistosoma mansoni	glucose transporter	0.0015	0.0071	0.0331
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0105	0.215	1
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0033	0.0481	0.8107
Brugia malayi	major facilitator superfamily protein	0.0015	0.0071	0.0331
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0481	0.1973

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 619871