Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.2772 | 0.5 | |
Echinococcus multilocularis | lamin | 0.0027 | 0.2772 | 0.2772 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.2772 | 0.2772 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.2772 | 0.2772 |
Onchocerca volvulus | 0.0027 | 0.2772 | 0.5 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.2772 | 0.2772 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.2674 | 0.2674 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0285 | 0.0285 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.2772 | 0.2561 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.2772 | 0.2772 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.2772 | 0.2772 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.2772 | 0.2772 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 1 | 1 |
Echinococcus granulosus | lamin | 0.0027 | 0.2772 | 0.2772 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.2772 | 0.2772 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.2772 | 0.2561 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.