Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 1 | 1 |
Echinococcus granulosus | atp dependent rna helicase ddxx | 0.0006 | 0.0000000051486 | 0.0000000051486 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.3902 | 0.3902 |
Echinococcus multilocularis | lamin | 0.0027 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.3204 | 0.3204 |
Plasmodium vivax | DEAD/DEAH box helicase, putative | 0.0006 | 0.0000000051486 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 1 | 1 | |
Plasmodium falciparum | ATP-dependent RNA helicase DBP1, putative | 0.0006 | 0.0000000051486 | 0.5 |
Giardia lamblia | ATP-dependent RNA helicase-like protein | 0.0006 | 0.0000000051486 | 0.5 |
Trypanosoma cruzi | ATP-dependent RNA helicase HEL67 | 0.0006 | 0.0000000051486 | 0.5 |
Echinococcus granulosus | lamin | 0.0027 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 1 | 1 |
Toxoplasma gondii | DEAD (Asp-Glu-Ala-Asp) box polypeptide DDX3X | 0.0006 | 0.0000000051486 | 0.5 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0006 | 0.0000000051486 | 0.5 |
Schistosoma mansoni | lamin | 0.0027 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.976 | 0.976 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0006 | 0.0000000051486 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.2964 | 0.2964 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0006 | 0.0000000051486 | 0.5 |
Trypanosoma cruzi | ATP-dependent RNA helicase HEL67 | 0.0006 | 0.0000000051486 | 0.5 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.3204 | 0.3204 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 1 | 1 |
Trypanosoma brucei | ATP-dependent RNA helicase HEL67 | 0.0006 | 0.0000000051486 | 0.5 |
Schistosoma mansoni | lamin | 0.0027 | 1 | 1 |
Giardia lamblia | DEAD box RNA helicase Vasa | 0.0006 | 0.0000000051486 | 0.5 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.3204 | 0.3204 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.2964 | 0.2964 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.3902 | 0.3902 |
Mycobacterium ulcerans | ATP-dependent RNA helicase, RhlE1 | 0.0006 | 0.0000000051486 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.