Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Dual oxidase homolog | 0.0329 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0349 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0086 | 0.2019 | 0.1866 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0323 | 0.9795 | 0.9791 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0329 | 1 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0435 | 0.0252 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0435 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0241 | 0.7116 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0435 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0349 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0435 | 0.0252 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0349 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0435 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0435 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0435 | 0.0252 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0435 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0349 | 0.0164 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0435 | 0.0252 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0435 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0329 | 1 | 1 |
Onchocerca volvulus | 0.0329 | 1 | 1 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0435 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0435 | 0.0252 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0329 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0349 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0435 | 0.0252 |
Echinococcus multilocularis | snurportin 1 | 0.0323 | 0.9795 | 0.9791 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0435 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0435 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0435 | 0.0252 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0188 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0435 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0329 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0435 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0349 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0435 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0329 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0329 | 1 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0435 | 1 |
Echinococcus granulosus | peroxidasin | 0.0329 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0435 | 0.5 |
Brugia malayi | Peroxidasin | 0.0329 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0435 | 0.0252 |
Brugia malayi | Animal haem peroxidase family protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0435 | 0.0252 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0435 | 0.0252 |
Brugia malayi | Animal haem peroxidase family protein | 0.0329 | 1 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0435 | 0.0252 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0349 | 0.0164 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0435 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0349 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0435 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0435 | 1 |
Onchocerca volvulus | 0.0329 | 1 | 1 | |
Onchocerca volvulus | Peroxidase homolog | 0.0329 | 1 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0435 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0329 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0323 | 0.9795 | 0.9791 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0329 | 1 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0435 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0435 | 1 |
Schistosoma mansoni | peroxidasin | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0435 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0435 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0435 | 0.0252 |
Onchocerca volvulus | 0.0329 | 1 | 1 | |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0435 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0329 | 1 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0323 | 0.9795 | 0.9791 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0349 | 0.0164 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.