Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0627 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3164 | 0.3164 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1993 | 0.2892 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3164 | 0.4591 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.2267 | 0.3289 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1993 | 0.1993 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3164 | 0.3164 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3164 | 0.4591 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0627 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3164 | 0.4591 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1993 | 0.1993 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0627 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.2267 | 0.3289 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3164 | 0.4591 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1993 | 0.2892 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3164 | 0.3164 |
Echinococcus multilocularis | geminin | 0.0164 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0627 | 0.091 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1218 | 0.1218 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1993 | 0.1993 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0627 | 0.091 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.6892 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3164 | 0.3164 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0627 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.6892 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2267 | 0.3289 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0627 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1993 | 0.1993 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0627 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1993 | 0.1993 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3164 | 0.3164 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1993 | 0.1993 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3164 | 0.3164 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3164 | 0.3164 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0033 | 0.0048 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3164 | 0.4591 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.2267 | 0.3289 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0627 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1993 | 0.1993 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3164 | 0.4591 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.6892 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1218 | 0.1767 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0627 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1218 | 0.1767 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.