Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0179 | 0.1731 | 0.0703 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0146 | 0.1303 | 0.1612 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.0687 | 0.2467 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0191 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 0.2786 | 0.684 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 0.2786 | 0.684 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.027 | 0.0968 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0191 | 0.5 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0299 | 0.3329 | 0.5 |
Mycobacterium tuberculosis | UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) | 0.0583 | 0.7088 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0258 | 0.2786 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0179 | 0.1731 | 0.0703 |
Mycobacterium leprae | Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) | 0.0583 | 0.7088 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0258 | 0.2786 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.0687 | 0.1659 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0146 | 0.1303 | 0.1612 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 0.2786 | 0.684 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.027 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0185 | 0.1815 | 0.7131 |
Mycobacterium ulcerans | UDP-galactopyranose mutase Glf | 0.0583 | 0.7088 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.2468 | 0.8738 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0185 | 0.1815 | 0.1656 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0234 | 0.2468 | 0.2322 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 0.2786 | 0.684 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0234 | 0.2468 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 0.2786 | 0.684 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0191 | 0.7066 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0299 | 0.3329 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 0.2786 | 0.684 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0169 | 0.161 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.2717 | 0.9726 |
Brugia malayi | hypothetical protein | 0.0234 | 0.2468 | 0.886 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0191 | 0.7066 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.3329 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0253 | 0.2717 | 0.9753 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.