Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0085 | 0.0384 | 0.0384 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | opsin-like receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | G protein-coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | g-protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | neuropeptide F receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | allatostatin A receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.049 | 0.302 | 0.302 |
Schistosoma mansoni | amine GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | fmrfamide receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | ORL1-like opioid receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | myosin xvIII | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0036 | 0.0064 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0089 | 0.041 | 0.041 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0477 | 0.2932 | 0.2932 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | histamine h1 receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1563 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | fmrfamide receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1036 | 0.6568 | 0.6568 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.041 | 0.041 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0089 | 0.041 | 0.041 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | g protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | larval opioid receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | g protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Dopamine receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | CMGC/MAPK/JNK protein kinase | 0.1563 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0089 | 0.041 | 0.041 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0477 | 0.2932 | 0.2932 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | amine GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | allatostatin A receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Serotonin receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | amine GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0183 | 0.102 | 0.102 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0477 | 0.2932 | 0.2932 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.102 | 0.102 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Schistosoma mansoni | opsin-like receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | serotonin receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | g protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | amine GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1036 | 0.6568 | 0.6568 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | somatostatin receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | opsin-like receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | g protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | g protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Brugia malayi | GnHR receptor homolog | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | FTZ F1 alpha | 0.0417 | 0.2544 | 0.2544 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Dopamine receptor protein 2 | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | serotonin receptor | 0.0183 | 0.102 | 0.102 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | sex peptide receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | G-protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | follicle stimulating hormone receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | fmrfamide receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | amine GPCR | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0089 | 0.041 | 0.041 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.049 | 0.302 | 0.302 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | G-protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | putative neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | sex peptide receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | c Jun NH2 terminal kinase | 0.1563 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | AKH receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0477 | 0.2932 | 0.2932 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Brugia malayi | Dopamine receptor protein 1 | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | adenoreceptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | neuropeptide receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | orexin receptor type 2 | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Serotonin receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | g protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0183 | 0.102 | 0.102 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.049 | 0.302 | 0.302 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0219 | 0.1257 | 0.1257 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0089 | 0.041 | 0.041 |
Echinococcus multilocularis | serotonin receptor | 0.0183 | 0.102 | 0.102 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.102 | 0.102 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | biogenic amine receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | neuropeptide s receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | sulfakinin receptor protein | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | biogenic amine receptor | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0036 | 0.0064 | 1 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | RE15519p | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0064 | 0.0064 |
Onchocerca volvulus | 0.0036 | 0.0064 | 1 | |
Schistosoma mansoni | biogenic amine receptor | 0.0036 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0036 | 0.0064 | 0.0064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | neuropeptide F receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0089 | 0.041 | 0.041 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0036 | 0.0064 | 0.0064 |
Brugia malayi | Melatonin receptor type 1A | 0.0036 | 0.0064 | 0.0064 |
Echinococcus granulosus | c-Jun N-terminal kinases | 0.1563 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0036 | 0.0064 | 0.0064 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0036 | 0.0064 | 0.0064 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Estrogenic effect (functional) | = 33 % | Estrogenicity in rats following 3 x 0.1 mg s.c. over 72h. | ChEMBL. | 2754694 |
Inhibition (functional) | = 0 % | Inhibition of E2 effects in rats by 0.1 mg s.c. | ChEMBL. | 2754694 |
Inhibition (functional) | = 60 % | Percentage inhibition of uterotrophic effects of estradiol in vivo following 100 ug i.p. | ChEMBL. | 3981542 |
Inhibition (functional) | = 60 % | Percentage inhibition of uterotrophic effects of estradiol in vivo following 100 ug i.p. | ChEMBL. | 3981542 |
RBA (binding) | < 0.001 | Relative binding affinity calculated as the ratio of molar concentration of Estrogen receptor beta | ChEMBL. | 3981542 |
RBA (binding) | = 0.06 g | Relative binding against estrogen receptor of rat uterine cytosol by [2-4-3H] estradiol. | ChEMBL. | 2754694 |
RBA (binding) | = 0.06 g | Relative binding against estrogen receptor of rat uterine cytosol by [2-4-3H] estradiol. | ChEMBL. | 2754694 |
Uterine weight (functional) | = 22.2 g | Uterotrophic effects in rats following 3 x 0.1 mg s.c. over 72h. | ChEMBL. | 2754694 |
Uterine weight (functional) | = 70.4 g | Anti-uterotrophic effects in rats following 3 x 0.1 mg s.c. over 72h. | ChEMBL. | 2754694 |
Uterine weight (functional) | = 3.2 mg | In vivo uterotrophic activity (uterine weight) in immature mice. | ChEMBL. | 3981542 |
Uterine weight (functional) | = 3.2 mg | In vivo uterotrophic activity (uterine weight) in immature mice. | ChEMBL. | 3981542 |
Uterine weight (functional) | = 13.6 mg | In vivo anti-uterotrophic activity in mice following 1 ug estradiol i.p. | ChEMBL. | 3981542 |
Uterine weight (functional) | = 13.6 mg | In vivo anti-uterotrophic activity in mice following 1 ug estradiol i.p. | ChEMBL. | 3981542 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.