Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.02 | 0.037 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0598 | 0.0766 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0598 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.4553 | 0.8437 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.4553 | 0.8377 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0598 | 0.1108 |
Entamoeba histolytica | aminopeptidase, putative | 0.0073 | 0.5396 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.4553 | 0.4442 |
Trypanosoma brucei | aspartyl aminopeptidase, putative | 0.0073 | 0.5396 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0598 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.4553 | 0.4442 |
Trichomonas vaginalis | Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase | 0.0073 | 0.5396 | 1 |
Plasmodium falciparum | M18 aspartyl aminopeptidase | 0.0073 | 0.5396 | 1 |
Trypanosoma cruzi | aspartyl aminopeptidase, putative | 0.0073 | 0.5396 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.4553 | 0.8437 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.02 | 0.037 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.4553 | 0.4442 |
Schistosoma mansoni | lipoxygenase | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.02 | 0.037 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.02 | 0.037 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.4553 | 0.8377 |
Echinococcus granulosus | aspartyl aminopeptidase | 0.0073 | 0.5396 | 0.5302 |
Schistosoma mansoni | lipoxygenase | 0.0083 | 0.6459 | 0.6387 |
Mycobacterium tuberculosis | Probable aminopeptidase PepC | 0.0073 | 0.5396 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0598 | 0.0766 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0598 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0598 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MH, Family M20 | 0.0073 | 0.5396 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0598 | 1 |
Brugia malayi | RNA binding protein | 0.0064 | 0.4553 | 0.8377 |
Plasmodium vivax | M18 aspartyl aminopeptidase, putative | 0.0073 | 0.5396 | 1 |
Trichomonas vaginalis | Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase | 0.0073 | 0.5396 | 1 |
Trypanosoma brucei | aspartyl aminopeptidase, putative | 0.0073 | 0.5396 | 0.5 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.02 | 0.037 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0598 | 0.0766 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.4553 | 0.4442 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0598 | 0.1108 |
Loa Loa (eye worm) | aspartyl aminopeptidase | 0.0073 | 0.5396 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0598 | 0.1108 |
Entamoeba histolytica | aspartyl aminopeptidase, putative | 0.0073 | 0.5396 | 1 |
Onchocerca volvulus | 0.0024 | 0.0598 | 1 | |
Schistosoma mansoni | aspartyl aminopeptidase (M18 family) | 0.0073 | 0.5396 | 0.5302 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0598 | 0.1108 |
Leishmania major | aspartyl aminopeptidase, putative,metallo-peptidase, Clan MH, Family M20 | 0.0073 | 0.5396 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0598 | 1 |
Echinococcus multilocularis | aspartyl aminopeptidase | 0.0073 | 0.5396 | 0.5302 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.4553 | 0.4442 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0598 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.4553 | 0.8437 |
Trichomonas vaginalis | Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase | 0.0073 | 0.5396 | 1 |
Brugia malayi | Aspartyl aminopeptidase | 0.0073 | 0.5396 | 1 |
Schistosoma mansoni | aspartyl aminopeptidase (M18 family) | 0.0073 | 0.5396 | 0.5302 |
Mycobacterium leprae | PROBABLE AMINOPEPTIDASE PEPC | 0.0073 | 0.5396 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.4553 | 0.4442 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.4553 | 0.4442 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0598 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.5396 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0598 | 0.1108 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.5396 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.