Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | sodium- and chloride- dependent transporter | 0.017 | 0.7345 | 0.5 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0051 | 0.0861 | 0.1063 |
Loa Loa (eye worm) | serotonin transporter b | 0.017 | 0.7345 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0051 | 0.0861 | 0.1063 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.7345 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0176 | 0.7674 | 0.9482 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0176 | 0.7674 | 0.9482 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.017 | 0.7345 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0184 | 0.8094 | 1 |
Echinococcus multilocularis | serotonin transporter | 0.017 | 0.7345 | 0.9075 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0043 | 0.0419 | 0.0518 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0184 | 0.8094 | 1 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0051 | 0.0861 | 0.1063 |
Loa Loa (eye worm) | norepinephrine transporter | 0.017 | 0.7345 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0051 | 0.0861 | 0.1063 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.017 | 0.7345 | 0.7229 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0043 | 0.0419 | 0.0518 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0051 | 0.0861 | 0.1063 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0051 | 0.0861 | 0.1063 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0051 | 0.0861 | 0.1063 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.7345 | 1 |
Onchocerca volvulus | 0.017 | 0.7345 | 0.5 | |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0051 | 0.0861 | 0.1063 |
Loa Loa (eye worm) | hypothetical protein | 0.017 | 0.7345 | 1 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0043 | 0.0419 | 0.0518 |
Echinococcus granulosus | serotonin transporter | 0.017 | 0.7345 | 0.9075 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0051 | 0.0861 | 0.1063 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0168 | 0.7233 | 0.8937 |
Echinococcus granulosus | glutamate receptor 2 | 0.0051 | 0.0861 | 0.1063 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.017 | 0.7345 | 1 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0168 | 0.7233 | 0.8937 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.017 | 0.7345 | 0.7229 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.