Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0068 | 0.5281 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1873 | 0.3598 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.1873 | 0.3546 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0068 | 0.5281 | 0.5281 |
Brugia malayi | Augmenter of liver regeneration | 0.0068 | 0.5281 | 0.5281 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1873 | 0.1873 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.1873 | 0.1873 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0068 | 0.5281 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.1873 | 0.1873 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.5205 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1873 | 0.3598 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0068 | 0.5281 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.1873 | 0.3546 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0068 | 0.5281 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.8076 | 0.8076 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.1873 | 0.3546 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0068 | 0.5281 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.1873 | 0.3546 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0068 | 0.5281 | 1 |
Onchocerca volvulus | Sulfhydryl oxidase homolog | 0.0011 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1873 | 0.3598 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 1 | 1 |
Onchocerca volvulus | Sulfhydryl oxidase homolog | 0.0011 | 0 | 0.5 |
Onchocerca volvulus | Sulfhydryl oxidase homolog | 0.0011 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.8076 | 0.8076 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.1873 | 0.3546 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.1873 | 0.3546 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.5205 | 0.5205 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.5205 | 0.5205 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.1873 | 0.1873 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0068 | 0.5281 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.8076 | 0.8076 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.8076 | 0.8076 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0068 | 0.5281 | 1 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0068 | 0.5281 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0068 | 0.5281 | 1 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0068 | 0.5281 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1873 | 0.3598 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.