Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0 | 0.5 |
Onchocerca volvulus | 0.0032 | 0.4403 | 0.5 | |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0056 | 0.8268 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4403 | 0.4403 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0056 | 0.8268 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.04 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.8268 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0127 | 0.0127 |
Trypanosoma brucei | protein kinase, putative | 0.0056 | 0.8268 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.8268 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.04 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4688 | 0.5299 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.8869 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0056 | 0.8268 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0056 | 0.8268 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0056 | 0.8268 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.8268 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.4715 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Brugia malayi | MAP kinase sur-1 | 0.0056 | 0.8268 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0056 | 0.8268 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0056 | 0.8268 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 0.0635 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0056 | 0.8268 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 0.0635 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0056 | 0.8268 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0056 | 0.8268 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 0.0635 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0056 | 0.8268 | 0.8268 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4688 | 0.5299 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.4729 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0056 | 0.8268 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0056 | 0.8268 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.8268 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0056 | 0.8268 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.