Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0035 | 0.0009 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0406 | 0.2055 |
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 0.1973 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0009 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0009 | 0.0045 |
Brugia malayi | phenylalanyl (f) trna synthetase protein 1 | 0.0451 | 0.1973 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.0406 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.067 | 0.3008 | 1 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.013 | 0.046 | 0.2299 |
Echinococcus granulosus | microtubule associated protein 2 | 0.067 | 0.3008 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0009 | 0.0045 |
Treponema pallidum | phenylalanyl-tRNA synthetase subunit alpha | 0.0451 | 0.1973 | 0.5 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase mitochondrial | 0.013 | 0.046 | 0.1531 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0009 | 0.0029 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0223 | 0.0899 | 0.089 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0009 | 0.0045 |
Mycobacterium ulcerans | phenylalanyl-tRNA synthetase subunit alpha | 0.2149 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0621 | 0.2064 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0621 | 0.2064 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0406 | 0.2055 |
Trypanosoma brucei | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0451 | 0.1973 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.067 | 0.3008 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0072 | 0.0367 |
Plasmodium falciparum | phenylalanine--tRNA ligase alpha subunit | 0.0451 | 0.1973 | 1 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase alpha chain B | 0.0451 | 0.1973 | 0.655 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0072 | 0.0367 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0009 | 0.0029 |
Toxoplasma gondii | Ferredoxin-fold anticodon binding domain-containing protein | 0.013 | 0.046 | 0.2299 |
Brugia malayi | phenylalanyl-tRNA synthetase, mitochondrial precursor, putative | 0.013 | 0.046 | 0.2333 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.013 | 0.046 | 0.2299 |
Echinococcus granulosus | phenylalanyl tRNA synthetase | 0.013 | 0.046 | 0.1506 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0009 | 0.0045 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0009 | 0.0029 |
Echinococcus granulosus | phenylalanyl tRNA synthetase alpha chain B | 0.0451 | 0.1973 | 0.655 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0009 | 0.0045 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0009 | 0.0045 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0009 | 0.0029 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.0451 | 0.1973 | 0.656 |
Schistosoma mansoni | phenylalanyl-tRNA synthetase subunit alpha | 0.013 | 0.046 | 0.1531 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0406 | 0.2055 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0009 | 0.0045 |
Entamoeba histolytica | phenylalanyl-tRNA synthetase alpha subunit, putative | 0.0451 | 0.1973 | 1 |
Mycobacterium leprae | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.032 | 0.1357 | 1 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0451 | 0.1973 | 1 |
Echinococcus multilocularis | phenylalanyl tRNA synthetase | 0.013 | 0.046 | 0.1506 |
Loa Loa (eye worm) | phenylalanyl-tRNA synthetase | 0.013 | 0.046 | 0.2333 |
Mycobacterium tuberculosis | Probable phenylalanyl-tRNA synthetase, alpha chain PheS | 0.2149 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0072 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0009 | 0.0045 |
Plasmodium vivax | phenylalanine--tRNA ligase, putative | 0.013 | 0.046 | 0.2299 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0072 | 0.0367 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.0406 | 1 |
Wolbachia endosymbiont of Brugia malayi | phenylalanyl-tRNA synthetase subunit alpha | 0.2149 | 1 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0009 | 0.0045 |
Giardia lamblia | Phenylalanyl-tRNA synthetase alpha chain | 0.0451 | 0.1973 | 0.5 |
Trypanosoma cruzi | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0451 | 0.1973 | 1 |
Plasmodium vivax | phenylalanine--tRNA ligase alpha subunit, putative | 0.0451 | 0.1973 | 1 |
Trichomonas vaginalis | phenylalanyl-tRNA synthetase alpha chain, putative | 0.013 | 0.046 | 0.2299 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0009 | 0.0045 |
Leishmania major | phenylalanyl-tRNA synthetase alpha chain, putative | 0.0451 | 0.1973 | 1 |
Echinococcus multilocularis | geminin | 0.0164 | 0.0621 | 0.2041 |
Echinococcus granulosus | geminin | 0.0164 | 0.0621 | 0.2041 |
Toxoplasma gondii | phenylalanyl-tRNA synthetase alpha chain A, putative | 0.0451 | 0.1973 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0009 | 0.0045 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.