Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | methionyl-tRNA synthetase, putative | 0.0235 | 0.3588 | 0.5 |
Brugia malayi | methionyl-tRNA synthetase | 0.0235 | 0.3588 | 0.5 |
Loa Loa (eye worm) | multisynthetase complex auxiliary component p43 | 0.0203 | 0.2908 | 1 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0202 | 0.2882 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0539 | 1 | 1 |
Treponema pallidum | methionyl-tRNA synthetase | 0.0235 | 0.3588 | 0.5 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0066 | 0 | 0.5 |
Chlamydia trachomatis | methionine--tRNA ligase | 0.0202 | 0.2882 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0539 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0539 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.