Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | polypeptide deformylase-like protein, putative | 0.0086 | 0.2594 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0086 | 0.2594 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0086 | 0.2594 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0225 | 0.9136 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0086 | 0.2594 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0225 | 0.9136 | 0.5 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0 | 0.5 |
Plasmodium falciparum | peptide deformylase | 0.0225 | 0.9136 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0225 | 0.9136 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.0225 | 0.9136 | 1 |
Chlamydia trachomatis | peptide deformylase | 0.0225 | 0.9136 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.0225 | 0.9136 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0244 | 1 | 0.5 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.8611 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0 | 0.5 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0086 | 0.2594 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.8611 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0086 | 0.2594 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.0225 | 0.9136 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0086 | 0.2594 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0225 | 0.9136 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.