Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Leishmania major | C-8 sterol isomerase-like protein | 0.028 | 0.7871 | 1 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0295 | 0.8316 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.7871 | 0.7615 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0352 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.028 | 0.7871 | 0.7615 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0295 | 0.8316 | 1 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0295 | 0.8316 | 0.5 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.0295 | 0.8316 | 0.8114 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0295 | 0.8316 | 0.8114 |
Plasmodium falciparum | hexose transporter | 0.0052 | 0.107 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.107 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.028 | 0.7871 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.028 | 0.7871 | 1 |
Plasmodium vivax | hexose transporter | 0.0052 | 0.107 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0052 | 0.107 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.3788 | 0.3043 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0052 | 0.107 | 0.0292 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0295 | 0.8316 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.