Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0117 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0691 | 0.643 | 0.643 |
Echinococcus multilocularis | calcium release activated calcium channel | 0.101 | 1 | 1 |
Onchocerca volvulus | 0.0117 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0691 | 0.643 | 0.643 |
Onchocerca volvulus | 0.0117 | 0 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0691 | 0.643 | 0.643 |
Loa Loa (eye worm) | hypothetical protein | 0.0691 | 0.643 | 0.643 |
Brugia malayi | Carboxylesterase family protein | 0.0691 | 0.643 | 0.643 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0117 | 0 | 0.5 |
Schistosoma mansoni | Protein orai-1 | 0.101 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0691 | 0.643 | 0.643 |
Schistosoma mansoni | Protein orai-1 | 0.101 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0691 | 0.643 | 0.643 |
Loa Loa (eye worm) | carboxylesterase | 0.0691 | 0.643 | 0.643 |
Echinococcus granulosus | acetylcholinesterase | 0.0691 | 0.643 | 0.643 |
Echinococcus multilocularis | stromal interaction molecule 1 | 0.0224 | 0.1195 | 0.1195 |
Loa Loa (eye worm) | hypothetical protein | 0.101 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1195 | 0.1195 |
Schistosoma mansoni | hypothetical protein | 0.0121 | 0.0049 | 0.0049 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0117 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0691 | 0.643 | 0.643 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0117 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0117 | 0 | 0.5 |
Onchocerca volvulus | 0.0117 | 0 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0224 | 0.1195 | 0.1195 |
Echinococcus granulosus | calcium release activated calcium channel | 0.101 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0691 | 0.643 | 0.643 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0117 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0691 | 0.643 | 0.643 |
Onchocerca volvulus | 0.0117 | 0 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0691 | 0.643 | 0.643 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0419 | 0.3386 | 0.3386 |
Echinococcus granulosus | stromal interaction molecule 1 | 0.0224 | 0.1195 | 0.1195 |
Onchocerca volvulus | 0.0117 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.