Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | GHMP kinase, N-terminal domain-containing protein | 0.0075 | 0.2449 | 1 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.3994 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.3994 | 0.5 |
Treponema pallidum | galactokinase | 0.014 | 0.8167 | 1 |
Trypanosoma cruzi | galactokinase, putative | 0.016 | 1 | 1 |
Echinococcus multilocularis | N acetylgalactosamine kinase | 0.0075 | 0.2449 | 0.2298 |
Echinococcus granulosus | N acetylgalactosamine kinase | 0.0075 | 0.2449 | 0.2298 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.3994 | 1 |
Entamoeba histolytica | galactokinase, putative | 0.016 | 1 | 1 |
Trypanosoma brucei | galactokinase-like protein, putative | 0.0107 | 0.5256 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Schistosoma mansoni | mevalonate kinase | 0.0049 | 0.0197 | 0.0493 |
Mycobacterium tuberculosis | Probable galactokinase GalK (galactose kinase) | 0.016 | 1 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.3994 | 0.7506 |
Loa Loa (eye worm) | galactokinase | 0.0075 | 0.2449 | 0.5932 |
Trypanosoma cruzi | galactokinase, putative | 0.016 | 1 | 1 |
Echinococcus multilocularis | galactokinase | 0.016 | 1 | 1 |
Mycobacterium ulcerans | galactokinase | 0.016 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.3994 | 0.3874 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.3994 | 0.3874 |
Trypanosoma cruzi | galactokinase-like protein, putative | 0.014 | 0.8167 | 0.813 |
Mycobacterium leprae | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) | 0.0049 | 0.0197 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Trypanosoma cruzi | galactokinase, putative | 0.014 | 0.8167 | 0.813 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.3994 | 0.3874 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Leishmania major | galactokinase-like protein | 0.016 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.3994 | 0.3874 |
Wolbachia endosymbiont of Brugia malayi | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0049 | 0.0197 | 0.5 |
Brugia malayi | galactokinase family protein | 0.0075 | 0.2449 | 0.5932 |
Schistosoma mansoni | galactokinase | 0.0075 | 0.2449 | 0.6132 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.3994 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.3994 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.3994 | 0.3874 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.3994 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.